Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare primary liver cancer that occurs in young adults, and its biology is not well known. We present a 21-year-old woman with metastatic liver cancer 6 months after undergoing embolization procedures for a typical hemangioma. The pathological ...
"It's crazy that I've been able to do this," said Elana Simon, describing her idea to study the extremely rare form of liver cancer that mostly hits adolescents and young adults. Making that idea work required a lot of help from real scientists: Her father, who runs a cellular biophysi...
As a rare and lethal liver cancer that disproportionately harms young adults, fibrolamellar carcinoma is nearly incurable. Surgery can remove the tumor, but no existing therapies are capable of reining in the cancer once it starts to spread throughout the body. Now, a new study demonstrates that...
Probing a rare tumour typeFIBROLAMELLAR hepatocellular carcinomaLIVER cancerDISEASES in young adultsThe article discusses a study regarding fibrolamellar hepatocellular carcinoma (FL-HCC), which is a liver tumour affecting adolescents and young adults.doi:10.1038/nrc3714Sarah SetonRogersNature Reviews Cancer...
Benign liver tumors are common. They do not spread to other areas of the body, and they usually do not pose a serious health risk. In fact, in most cases, benign liver tumors are not diagnosed because patients are asymptomatic. When they are detected, it’s usually because the person has...
doing to accelerate research and drive progress in the fight against rare diseases, like fibrolamellar carcinoma (Fibrolamellar or FLC). Fibrolamellar is an aggressive, ultra-rare liver cancer affecting children and young adults, with no curative therapies and an alarmingly low...
Seth is a founder of Our Odyssey, an organization that connects young adults impacted by a rare or chronic condition with social and emotional support. He also advocates for the Huntington disease community through speaking, fundraising, and other volunteer efforts. Host Andra Stratton Since her ...
Burkitt lymphoma (BL) is an uncommon form of lymphoma in adults. In this disease, extensive involvement of the omentum and the peritoneum is rare. We present this case with ascites because it is such a rare and overlooked clinical presentation of BL.A previously healthy 20-year-old man was...
Cardiometabolic diseases are the leading cause of death worldwide. Despite a known genetic component, our understanding of these diseases remains incomplete. Here, we analyzed the contribution of rare variants to 57 diseases and 26 cardiometabolic traits
The scientists recommend that people with advanced-stage fibrolamellar hepatocellular carcinoma, which mostly affects teenagers and young adults, receive regular neuroimaging scans because of the tumor's apparent ability to metastasize to the brain. Solid tumors, including those in the liver, don't usua...