Alport syndrome is a genetic kidney disease that causes worsening of kidney function over time, often progressing to kidney failure. Some types of Alport s
38 Ridley AJ, Hall A: The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992; 70: 389–399. 39 Noma K, Kihara Y, Higashi Y: Striking crosstalk of ROCK signaling with endothelial function. J Cardiol 2012...
Some strengths are worth mentioning as well. To our knowledge, this is the first study to explore how HDGECs define their QoL. We used both manifest and latent content analysis to provide a first in-depth look into the components of HDGECs’ QoL definitions, as well as its underlying mean...
It is worth noting that genetic information for target therapies can affect graft survival following transplantation. It is common for a diagnosis of rare kidney disease to be delayed or even missed entirely, which is probably an underrecognized cause of graft dysfunction. Our findings revealed that...
3). Though these findings are an indication that the inclusion of more data alone may not lead to better performance, it is worth noting that these four largest sites used for the independent model training represent comprehensive cancer centers (compared to hospitals in community settings) with ...
Finch AJ, Hilcenko C, Basse N, Drynan LF, Goyenechea B, Menne TF, Gonzalez FA, Simpson P, D'Santos CS, Arends MJ: Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev. 2011, 25: 917-929. 10.1101/gad.623011. PubMed Central CAS...
It is worth noting that PubMed was searched in addition to MEDLINE, as MEDLINE is a subset of PubMed which allows more specific searching but can return different results [45]. A search was also conducted of grey literature using the databases GreyLit and OpenGrey. Reference lists of ...
However, a few recent advances are worth mentioning. The origin of pathological fibroblast foci within the IPF lesion remains puzzling. Possibilities include differentiation of resident fibroblasts, recruitment of circulating fibroblast precursors and transdifferentiation of epithelial cells into pathological ...
Keyworth, Nottingham Sheard ER, Williams-Jones AE, Heiligmann M, Pederson C, Trueman DL (2012) Controls on the concentration of zirconium, niobium, and the rare earth elements in the Thor Lake rare metal deposit, Northwest Territories, Canada. Econ Geol 107:81–104 Article Google Scholar ...
Transthyretin amyloidosis is a progressive and eventually fatal disease primarily characterized by sensory, motor, and autonomic neuropathy and/or cardiomyopathy. Given its phenotypic unpredictability and variability, transthyretin amyloidosis can be dif