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Third, we asked if the use of chemical additives might bolster the sensitivity of LAMP. A recent study showed that glycine and taurine could improve the kinetics of the one-pot STOPCovid test22. However, it is unclear if the improvement occurs in the RT-LAMP reaction or in the Cas detect...
Rapid, accurate, and scalable testing systems for COVID-19 diagnosis are essential to control SARS-CoV-2, the novel coronavirus causing COVID-19 pandemic, and reopen society. The diagnosis of COVID-19 mainly relies on the detection of the coronavirus RNA. The gold standard testing system appro...
Because of COVID, there were some problems with Dài-Gòu. And I was also trying to adjust my body status. I had less sex. So, I didn’t see there was a need for me to continue using it (PrEP). (GD19, 27 yrs, former PrEP user, PrEP source: Dài-Gòu). All of these obstacl...
Antibody discovery is bottlenecked by the individual expression and evaluation of antigen-specific hits. Here, we address this bottleneck by developing a workflow combining cell-free DNA template generation, cell-free protein synthesis, and binding measu
Kyle:To build on what you just said, Dr. Mina, about what we really care about is a test that captures the contagious window for someone when they get COVID-19, you have a great graph that shows the viral dynamics and this huge spike. Could you explain that?
‐53 people would test positive for COVID‐19. Of these, 9 people (17%) would not have COVID‐19 (false positive result). ‐947 people would test negative for COVID‐19. Of these, 6 people (0.6%) would actually have COVID‐19 (false negative result). In people with no symptoms...
OMIC.ai has a web-based biomedical/AI platform used for open-source COVID-19 research. Users currently log in via magic link, but the company would like to add an option where the person is identified via voice through the browser. Ideally the company would generate a phrase for the user...
STOPCovid (93.1%, 188/202) and specificity (98.5%, 197/200)26. Lalli et al.developed an extraction-free RT-LAMP test for COVID-19 using saliva with colorimetric detection27. Lalli et al.achieved a slightly higher limit of detection than Saliva-Dry LAMP (59 copies/reaction or 21.6 ...
A rapid increase in COVID-19 cases was observed from the middle of November 2021 in Gauteng province, the economic hub of South Africa containing the cities of Tshwane (Pretoria) and Johannesburg. Specifically, rising case numbers and test positivity rates were first noticed in Tshwane, initially...