In addition, abnormal expression of IL-1β and TNF-α protein and mRNA was also significantly attenuated by oral administration of AcRE. Treatment with AcRE also significantly suppressed TMA-induced IL-4 and IL-13 cytokines and mRNA expression in vivo. Moreover, AcRE strongly suppressed TMA-...
In addition, PLGA has been shown to be capable of promoting the cellular uptake of peptides into the cytoplasm within 10 min of incubation [26]. The first aim of this study was to prepare a drug delivery system for novel Ran-GTPase inhibitory peptides, designed specifically to interact with...