Mechanism of action The toxic mechanism remains to be elucidated, and the apparent lack of a reproducible dose response relations...Penny, D. , Henderson, S. M. & Brown, P. J. ( 2003 ) Raisin poisoning in a dog . Veterinary...
production of proinflammatory cytokines by macrophages stimulated withlipopolysaccharides(Bodet et al., 2008). Cranberry polyphenols are suggested to play a role in reducing the release of bacterial toxic products.Figure 30.1illustrates the mechanisms by which cranberry preventsperiodontitis(Bodet et al., ...
Prior to the onset of vomiting, all dogs were healthy, had no previous history of renal insufficiency, and had no exposure to other potentially nephrotoxic agents. This case series describes the clinical course and various treatment modalities used in the 4 dogs. New or unique information ...
All dogs had degeneration or necrosis (or both) of proximal renal tubules with basement membranes remaining intact, and epithelial regeneration was observed in 5 out of 10 cases. Mineralized tubular debris or granular to proteinaceous casts (or both) were present in all cases. A golden-brown, ...