Serum TSH has a tropic effect on thyroid nodules and suppression of TSH concentration by administration of exogenous thyroxine may interfere with the growth of established nodules, as well as the formation of new thyroid nodules [26–29]. TSH suppression is also associated with a decreased ...
The eight hypothyroid patients had normal glutathione S-transferase values at presentation and all showed a significant increase in these after thyroxine replacement therapy. In three of these patients in whom standard doses of replacement therapy were associated with a raised free thyroxine (T4) ...