93. The compound of claim 90, wherein the compound is represented by the structural formula: or a pharmaceutically acceptable salt thereof. 94. The pharmaceutical composition of claim 91, wherein the compound is represented by the structural formula: or a pharmaceutically acceptable salt thereof.Des...
An alternative articulation of this claim is: The risk of simultaneous smoking and alcohol use, among individuals with moderate alcohol consumption, was akin to the total population's risk (hazard ratio, 27; 95% confidence interval, 15-39).Sentences are listed in this JSON schema according to ...
6. The compound of claim 1 wherein the compound of formula II is selected from the group consisting of 3-{5-[2-({(3R)-1-[(4-chlorophenyl)sulfonyl]piperidin-3-yl}amino)pyrimidin-4-yl]imidazo[2,1-b][1,3]thiazol-6-yl}phenyl carbamate, 3-{5-[2-({(3R)-1-[(4-chlorophenyl)sul...
This claim needs further confirmation, however, since the mutation used in this study, YY340/341FF, has only a moderate effect on C-Raf kinase activity [23] and the residual activity may suffice for its function. A more definitive examination will require a “knock in” of a mutation that...
My only rise to fame was to be able to claim that I was on the Whitley crew that crash-landed on Waddington’s dummy airfield.We had originally taken off for Cologne but had trouble with the starboard engine with the result that we were unable to reach any altitude. It was decided to...
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11. The method of claim 8, wherein said cellular transformation phenotype is induced by a ras oncogene product. Description: BACKGROUND OF THE INVENTION Field of the Invention The present invention relates, in general, to methods of inducing a therapeutic effect. In particular, the present invent...
31. The method of claim 29, wherein the cancer is a carcinoma. 32. The method of claim 31, wherein the carcinoma is squamous cell carcinoma. 33. The method of claim 31, wherein the carcinoma is adenoma or adenocarcinoma. 34. The method of claim 29, wherein the cancer is breast, ov...