Studies reported hazard ratios (HRs) with 95% confidence intervals (CIs) for the association between RKIP and overall survival (OS) and disease-free survival (DFS) in cancers of the digestive system were eligible, including esophageal cancer, gastric cancer, colorectal cancer and pancreatic cancer....
Moreover, this classifier distinguished patients with the worst OS and DFS, validating the CMS4 subtype. Taken together, the molecular and prognostic profile of CMS4 patients is reminiscent of a high-grade tumour budding phenotype, and we speculated an association between tumour cell budding and ...
Hook to a hole: A cell‐permeable bivalent inhibitor of protein prenyltransferases binds to the active pocket and delivers a small module compound onto an interface of protein–protein interactions with K‐Ras, allowing inhibition of posttranslational lipid modification of K‐Ras and association with...