Crystal structure of a chaperone-bound assembly intermediate of form I RuBisCO. Nat. Struct. Mol. Biol. 18, 875–880 (2011). Article CAS PubMed Google Scholar Hauser, T. et al. Structure and mechanism of the RuBisCO-assembly chaperone Raf1. Nat. Struct. Mol. Biol. 22, 720–728 (...
The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progressionArticle Open access Published: 21 March 2024 Volume 15, article number 2551, (2024) Cite this article Download PDF You have full access to this open access article ...
Formononetin ameliorates renal dysfunction, oxidative stress, inflammation, and apoptosis and upregulates Nrf2/HO-1 signaling in a rat model of gentamicin-induced nephrotoxicity Front. Pharmacol., 13 (2022), Article 916732 View in ScopusGoogle Scholar Bai et al., 2022 R. Bai, Y. Wang, Y. ...
Structure of the MRAS–SHOC2–PP1C phosphatase complex Article Open access 13 July 2022 References Matallanas, D. et al. Raf family kinases: old dogs have learned new tricks. Genes Cancer 2, 232–260 (2011). CAS PubMed PubMed Central Google Scholar Rapp, U. R. et al. Structure ...
All three RAF isoforms can form homo and heterodimers, which are crucial for kinase activity under normal physiological conditions79. The prevailing belief is that when RAS-GTP is activated, and scaffold complexes such as SHOC2-PP1C are present, they recruit autoinhibited RAF monomers to the cel...
Download PDF(file size ± 10Mb) Britain’s first black pilot The website of the RAF Museum honours Sergeant William Robinson Clarke, Britain’s first black pilot, who received his Wings on 26 April 1917. Read his storyhere. The story of the RAF’s answer to the Tuskegee Airmen written by...
Apoptosis, a form of programmed cell death, plays an essential role in the normal development and maintenance of cellular and tissue homeostasis in multicellular organisms [44, 45]. Two major apoptotic signaling pathways have been identified: an extrinsic pathway initiated by death receptors and an ...
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Download: Download full-size image Fig. 1. Effects of O-GlcNAcylation on EMT in HK2 cells. A, HK2 cells were treated with glucosamine at indicated concentrations, proteins were isolated and western blot was performed using indicated antibodies. B and C, HK2 cells were treated with vehicle or ...
Download: Download full-size image Fig. 5. Spatial distribution maps of (a) Temperature (b) Colour (c) Turbidity (d) EC (e) TSS (f) TDS. 3.2. Chemical parameters 3.2.1. pH, Hardness, BOD and COD pH is an important variable in evaluating the acid-base balance of water. It indicate...