ChemotherapyVoicePreservationLocalControlPurpose: To compare concurrent chemoradiotherapy with radiotherapy in T2N0 glottic cancer. Materials and Methods: Thirty nine patients were treated with radiotherapy alone. In detail, 30 patients treated between 1985 and 1995, and 9 patients treated between 1995 and...
chemotherapy, neoadjuvantImportance Induction chemotherapy plus concurrent chemoradiotherapy is recommended for locoregionally advanced nasopharyngeal carcinoma but is associated with higher rates of acute toxic effects and low compliance. Evidence on de-escalating treatment intensity after induction chemotherapy is...
Purpose: To evaluate the effect of adding one cycle of concomitant chemotherapy to curative radiotherapy on tumor control and toxicity in the treatment of anal cancer. Methods and Materials: One hundred twenty-five patients completed curative sphincter-conserving treatment, 57 with radiotherapy alone and...
Radiotherapy-induced prodrug activation provides an ideal solution to reduce the systemic toxicity of chemotherapy in cancer therapy, but the scope of the radiation-activated protecting groups is limited. Here we present that the well-established photoin
184 patients with squamous cell carcinoma of the cervix, FIGO stage IIB-IVA, were randomized to receive either two cycles of bleomycin, ifosfamide-mesna, and cis-platinum (BIP) chemotherapy (CT) followed by radiotherapy (RT) ("CT-RT group," n = 94) or RT alone (RT group, n = 90)....
Combined immunotherapy, radiotherapy, and/or chemotherapy can synergistically improve the outcome of patients treated for cancer14. However, selecting the best treatment according to liver disease and liver function is a challenge in patients with advanced HCC17. Whether immunotherapy combined with ...
BACKGROUND Prospective randomized and retrospective studies on adjunctive chemotherapy in patients with advanced locoregional nasopharyngeal carcinoma have yielded conflicting results and the role of chemotherapy in this disease had not been clearly defined. The authors report the results of a single instituti...
Cancer chemotherapy suffers from several challenges induced by severe side effects for patients due to the accumulation of anti-proliferative drugs in normal tissues. However, nanocarriers are able to partially compensate restrictions of conventional inefficient chemotherapy methods and increase available drugs...
The median survival time was 9 months and one─vear survivalrate was 34.9%, The difference of overall response rates was not statistically significant(P0. 25),but the survival was(P0. 005) in both groups. The major toxic effects of chemotherapy were gastrointestinal tract reaction─nausea , ...
The objectives of the study were to compare 2 doxorubicin-containing regimens and to compare RTx versus CTx as consolidation treatments for patients who had achieved a CR or a partial response (PR) of at least 75% after 6 cycles of chemotherapy. When this trial was initiated, response to ini...