In this Review, we discuss preclinical and clinical data that introduce radiotherapy as a tool to elicit or amplify clinically actionable signalling pathways in patients with cancer. Key points Targeted anticancer agents are commonly used in the treatment of various solid and haematological malignancies....
In this Review, we discuss preclinical and clinical data that introduce radiotherapy as a tool to elicit or amplify clinically actionable signalling pathways in patients with cancer. Key points Targeted anticancer agents are commonly used in the treatment of various solid and haematological malignancies....
Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer Article 24 November 2021 Harnessing progress in radiotherapy for global cancer control Article 25 September 2023 References Thariat, J., Hannoun-Levi, J. M., Sun Myint, A., Vuong, T. & Gerard, J. P....
Related to Radiotherapy, adjuvant:Adjuvant chemotherapy ad·ju·vant (ăj′ə-vənt) n. 1.A treatment that enhances an existing medical regimen, as a pharmacological agent added to a drug to increase or aid its effect. 2.An immunological agent that increases the antigenic response. ...
to cuproptosis. Therefore, we proposed a novel radiosensitization strategy focused on cuproptosis, using a copper-containing nanocapsule-like polyoxometalate as a paradigm. In an initial demonstration, we showed that the nanocapsule released copper ions in a controlled manner upon exposure to ionizing ...
Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells MAGE-A4 has been considered as an attractive cancer-testis (CT) antigen for tumour immunotherapy. It has been well accepted that T-helper type 1 (Th1) cell... T Ohkuri,D Wakita...
RT monitoring.EV-derived biomarkers show potential for assessing RT efficacy and predicting PCa recurrence.Radiation-induced EVs contribute to radioresistance and may serve as targets to enhance PCa radiosensitivity.Developing betterin vitroandin vivomodels will improve PCa RT and support clinical ...
a day, such as once in the morning and once in the afternoon with a 12-hour interval. Under specific circumstances, such as with rapidly growing squamous cell carcinomas of the head and neck skin, conventional fractionated radiotherapy is unable to control the tumour. Employing hyper-...
Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer. Nat. Rev. Clin. Oncol. 19, 114–131 (2022). Article CAS PubMed Google Scholar Andratschke, N. et al. European Society for Radiotherapy and Oncology and European Organisation for Research and Treatment of ...
Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer Targeted therapies have improved the outcomes of many patients with cancer, although many more lack targetable alterations or do not derive clinical benefit for other reasons. Radiotherapy can also provide benefit to ...