Radiotherapy was administered twice daily, 5 days a week, with a target dose of 1 Gy per fraction and with a minimum interval of 6 hours. A dose of 20 mg doxorubicin was administered intravenously 1 to 2 hours before the first radiotherapy session every week. Debulking surgery was feasible ...
Forty-seven patients with head and neck cancer were treated with thrice-a-day fractionation (200 rad Co″ three times per day, 5 days per week) to a total tumor dose of 4800–5400 rad over 9–11 days. Of this group, 22 advanced oral and pharyngo-laryngeal cancer patients had a 24-...
There are three dominant schemes of RT: conventional fractionation schemes (1.8~2.2 Gy/fraction, one fraction/day, 5 days/week for 3~7 weeks), hypofractionation including stereotactic radiosurgery (3~20 Gy/fraction, one fraction/day), and hyperfractionation (0.5~2.2 Gy/fraction, two fractions/da...
A 59-year-old male patient with rectal cancer 2 cm in diameter (T2) at the peritoneal reflection with suspicious left lateral node metastasis was treated with 400 mg of preoperative oral uracil and tegaful (UFT) for 5 weeks, 5 days a week in combination with concomitant radiotherapy of 45...
Primary lesions were treated with intensity-modulated radiotherapy at 50–50.4 Gy in 25–28 fractions 5 days/week. The gross tumor volume (GTV) included the primary tumor (GTV-P), metastatic lymph nodes (GTV-N), and metastatic lesions (GTV-M). The planning target volume was defined as...
Surgery, radiation therapy, or both, have been used for decades to achieve locoregional control; the most commonly used schedule when radiotherapy is given alone is 2 Gy in a single fraction per day, 5 days a week, for 7 weeks. Despite these treatments, the prognosis of patients with head...
a newly diagnosed anaplastic astrocytoma or glioblastoma and a Karnofsky performance score of 70 or higher were randomly assigned to receive supportive care only or supportive care plus radiotherapy (focal radiation in daily fractions of 1.8 Gy given 5 days per week, for a total dose of 50 Gy)...
The radioresistant C666-M2GY cells were from those survived C666-1 NPC cells treated with radiation 2 Gy a day, 5 days a week for four consecutive weeks. To confirm the radioresistance of these cell lines, C666-S8GY, C666-M2GY and control C666-1 cells were treated with 6 Gy ...
EBRT was originally delivered with conventional fractionated regimens (1.8-2.0 Gy/day, 5 days per week), performed over ≥8 weeks. While at this daily low dose range ionizing radiation is not lethal, it nonetheless produces potentially lethal DNA double-strand breaks (DSBs) [9], resolved by ...
RT was given in 2 Gy/fraction/day, 5 days a week for a total of 50-60 Gy. Pt characteristics include: median age 79 yrs (range 76-83), 23 men and 5 women, median performance status 1 (range 0-2). Histologic type: s q -12, adeno-15, large-1. Stage: I-8, II-0, III A...