Radical/Polar CrossoverRadicalsPhotoredox﹎ediated radical/polar crossover (RPC) processes provide unique solutions to challenging annulations. Herein, we describe an approach to the cyclopropanation of olefins that are embedded within bicyclic scaffolds. Whereas these systems are notoriously recalcitrant ...
Radical-polar crossover(RPC) reaction bridges the gap between one-and two-electron reactivities,thus providing an ideal solution to overcome the limitations of both radical and polar chemistry.In this manifold,organic electrochemistry provides a uniquely facile strategy to access a diverse array of rad...
Radical-polarcrossoverreactionswithawater-soluble tetrathiafulvalenederivative BalaramPatro, a MartinC.Merrett, a ScottD.Makin, a JohnA.Murphy a,∗ and KevinE.B.Parkes b a DepartmentofPureandAppliedChemistry,UniversityofStrathclyde,295CathedralSt,GlasgowG11XL,UK ...
Radical-polarcrossoverreactionsof vinylboronatecomplexes MarvinKischkewitz, 1 KazuhiroOkamoto, 2 ChristianMück-Lichtenfeld, 1 ArmidoStuder 1 * VinylboronicestersarevaluablesubstratesforSuzuki-Miyauracross-couplingreactions. However,boron-substitutedalkeneshavedrawnlittleattentionasradicalacceptors,and ...
Remote Hydroxylation through Radical Translocation and Polar CrossoverC‐H‐FunktionalisierungEntfernte FunktionalisierungHydroxylierungRedoxkatalyseSynthesemethodenMild conditions are reported for the hydroxylation of aliphatic CH bonds through radical translocation, oxidation to carbocation, and nucleophilic ...
Herein, we report the organophotoredox-catalyzed semipinacol rearrangement via radical-polar crossover (RPC). A phenothiazine-based organophotoredox catalyst facilitates the generation of an α-hydroxy non-benzylic alkyl radical followed by oxidation to the corresponding carbocation, which can be exploited...
Construction of a 6/5/9-membered tricyclic structure of cladiellins via radical-polar crossover reactionA three-component coupling reaction of structurally simple–was successfully applied for expeditious synthesis of the 6/5/9-membered tricyclic structureof cladieunicellin D () and klysimplexin U...
A. Synthesis of Highly Substituted Tetrahydrofurans by Catalytic Polar-Radical-Crossover Cycloadditions of Alkenes and Alkenols. Angew. Chem., Int. Ed. ... JMM Grandjean,DA Nicewicz - 《Angewandte Chemie International Edition》 被引量: 0发表: 2013年 Synthesis of highly substituted tetrahydrofuran...
A radical/polar crossover annulation between allyl‐substituted arenes and electron‐deficient alkenes is described. Cobalt‐catalyzed hydrogen atom transfer (HAT) facilitates tandem radical CC bond formation that generates functionalized tetralin products in the face of potentially problematic...
Further, secondary functionality may be included in either the radical precursor or acceptor, leading to subsequent formation of nitrogen heterocycles through a radical-polar crossover reaction.;We have found that photolysis of alkyl iodides in the presence of Mn 2(CO)10 leads to chemoselective ...