Brain NeoplasmsCobalt RadioisotopesMagnetic Resonance ImagingRadioisotope TeletherapyTime FactorsSequential MR imaging could provide information related to the pathological changes due to the application of external cytotoxic agents such as radiotherapy on the central nervous system. This paper describes the ...
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Radiation therapy is the most effective non-surgical treatment of primary brain tumors and metastases. Preclinical studies have provided valuable insights into pathogenesis of radiation-induced injury to the central nervous system. Radiation-induced brain injury can damage neuronal, glial and vascular compa...
Simultaneous in-field boost for patients with 1 to 4 brain metastasis/es treated with volumetric modulated arc therapy: a prospective study on quality-of-life Purpose To assess treatment toxicity and patients' survival/quality of life (QoL) after volumetric modulated arc therapy (VMAT) with simulta...
In boron neutron capture therapy (BNCT) the delivered dose to the patient depends both on the neutron beam characteristics and on the B body distribution which, in turn, is governed by the tumor specificity of the B drug-carrier. BNCT dosimetry is a complex matter due to the several interact...
Radiation therapy plays an integral role in the management of melanoma. Radiation therapy is infrequently needed for the treatment of the primary site, but there are occasions when it is appropriate. The role of adjuvant radiation therapy to resected nodal basins is becoming clearer from recent rand...
Commentary on stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of metastases: A randomized con... PURPOSE To test the hypothesis that increasing radiation dose delivered to men with early-stage prostate cancer improves clinical outcomes. PATIENTS ...
Proton minibeam radiation therapy (pMBRT) is a novel strategy which has already shown a remarkable reduction in neurotoxicity as to compared with standard proton therapy. Here we report on the first evaluation of tumor control effectiveness in glioma bearing rats with highly spatially modulated proton...
adiation therapy is used to treat a host of different diseases, although the most frequent use revolves around the treatment of cancer. Although effective—sufficient doses are able to effect virtually 100% cellular death of neoplastic cells—the toxicity of such therapy precludes administration of...
Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity The third-generation of EGFR-TKI osimertinib has been approved as a first-line therapy in NSCLC, representing the most successful advance in molecularly ta... Zhao, PengfeiZhang, Jiaxi...