Randomized studies evaluating the need for radiation therapy following lumpectomy in patients with DCIS from both the NSABP (B-17) and the EORTC (10853) demonstrated a local control benefit that was homogeneous across all treatment groups. In an era of medicine driven by characterization of tumors...
The study compared reports from 9,941 patients from practices across the state of Michigan who received radiation therapy following lumpectomy. Patients filled out standardsymptomreporting tools for four common side effects during their radiation treatment: pain, itchy skin, swelling and fatigue. At th...
Between January 1980 and December 1985, 121 patients with early breast cancer were treated in the Department of Radiation Oncology at Westmead Hospital by external beam irradiation and an iridium wire boost following "lumpectomy". After a median follow-up of 26 months, 14 patients have developed ...
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Objective: To evaluate the safety, cosmesis, and clinical outcome of intraoperative electron radiation therapy (IOERT) delivered prior to lumpectomy for early-stage breast cancer. Methods: From December 2008 to March 2012, 75 breast cancer patients (ages 34-66 years) were treated with IOERT dur...
Use of ultrasound to guide radiation boost planning following lumpectomy for carcinoma of the breast. Int J Radiat Oncol Biol Phys - Leonard, CL, et al.Leonard, C.; Harlow, C. L.; Coffin, C.; Drose, J.: Norton, L.; Kinzie, J. Use of ultrasound to guide radiation boost plan- ...
which removes only cancerous tissue and a thin margin of surrounding healthy cells instead of the entire breast. Current cancer guidelines for most women under 65 recommend following lumpectomy with radiation therapy, which targets stray cancer cells that might otherwise cause breast cancer to recur ...
Purpose: The purpose of this study was to determine the prognostic significance of cyclin D1 (cycD1) levels in ipsilateral breast tumor recurrence (IBTR) following lumpectomy and radiation therapy.Methods and Materials: A total of 98 patients (49 patients with IBTR and 49 matched cases without...
aFor example, preferences could play an important role in tonsillectomy rates, or choosing between mastectomy (removal of the breast) and lumpectomy followed by radiation therapy for the treatment of breast cancer, given that the two options yield similar long-term prognosis. 例如,特选可能演奏在扁...
Alvarado et al (2014) stated that the TARGIT-A Trial is an international randomized, prospective trial comparing IORT for equivalence to EBRT following lumpectomy for invasive breast cancer in selected low-risk patients; early results suggested that outcomes are similar. In addition to effectiveness...