combination therapyimmune modulatorsionizing irradiationradiotherapytumor-specific immunityObject. In this prospective study, the authors offered protocol-selected patients a combination of parenteral steroids, decompression surgery, and localized cooling to preserve viable spinal cord tissue and enhance functional...
Radiation therapy (RT) has historically been the most common approach used to achieve local tumor control in cancer patients. However, emerging evidences over the last decades suggest an important role for RT in modulating or amplifying the antitumor immune response upon induction of cancer cell deat...
The suppressive effect of low-dose radiation on cancer induction, growth, and metastasis and its immunologic mechanisms were analyzed. The present status of research in this field gives strong support to radiation hormesis in immunity with low-dose radiation as one of the mechanisms of cancer ...
A therapy for skin conditions, including psoriasis, eczema and vitiligo, that is composed of a plant-derived ultraviolet (UV)-sensitizer compound (psoralen), combined with UVA radiation (long wavelength radiation). Impetigo A common and highly contagious skin infection that mainly affects infants and...
Intraoperative radiation therapy— Radiation is delivered to a tumor during surgery. Radiosensitizers— These drugs increase radiation's damaging effect on cancer cells. Radioimmunotherapy— Radioactive substances are attached to antibodies, defensive chemicals made by the body's immune system. These antibo...
Although effective—sufficient doses are able to effect virtually 100% cellular death of neoplastic cells—the toxicity of such therapy precludes administration of such high amounts to patients. The nervous system is particularly sensitive to radiotherapy and is affected either directly or indirectly ...
Synergisitic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy 本发明提供了通过免疫子化合物增强免疫应答的优化方法和组合物,其用于治疗疾病,例如但不限于治疗患者的癌症,自体免疫疾...
Radiation therapyis one of the main treatment approaches for primary and secondary malignancies of the central nervous system (CNS). Prophylactic radiation to the brain or craniospinal axis is also performed in cancers with propensity to spread into the neuraxis, in order to prevent development of...
Since H@Gd-NCPs sensitized radiation could effectively induce ICD and activate immune responses against primary and distant CT26 colorectal tumors, we went on to determine the anti-metastatic effect in a spontaneous 4T1 metastatic breast cancer model (Fig. 9a). Compared with radiation therapy alone...
changes in irradiated cancer cells and immune cells in the TME under different RT regimens and describe existing and potential molecules that could be targeted to improve the therapeutic effects of RT. Overall, this review highlights the possibilities of synergistic therapy by building on existing ...