SophieDFossåSDOSLancetDearnaley DP, Khoo VS, Norman AR, Meyer L, Nanum A, et al. Comparison of radiation side-effects of conformal radiation and conventional radiation in prostate cancer: A randomized trial. Lancet 1999;353 (9149):267–72.
Late chronic side-effects limit the dose that can be given, and may be linked to the volume of normal tissues irradiated. Conformal radiotherapy allows a smaller amount of rectum and bladder to be treated, by shaping the high-dose volume to the prostate. We assessed the ability of this new...
Thus, the search for biological response modifiers that could potentiate the therapeutic effects of radiation and limit the occurrence of serious side effects is an important task in prostate cancer therapy. 1,25-Dihydroxyvitamin D(calcitriol), the active metabolite of vitamin D, and its analogues ...
The dose distribution to the rectum, delineated as solid organ, rectal wall and rectal surface, in 3D conformal (3D-CRT) and intensity-modulated radiotherapy treatment (IMRT) planning for localized prostate cancer was evaluated. In a retrospective planni
There seems to be, however, a tendency towards a 'return of the hypofractionating schedules' today in two of the most frequent cancers such as breast and prostate cancer. New hypofractionated schedules have been proposed due to new radiobiological data, suggesting high fractionation sensitivity of ...
Objectives: To report toxicity (primary endpoint) and biochemical disease-free survival (BDFS) outcomes of a phase II trial evaluating ultra-hypofractionated radiation therapy (UHRT) focusing on unfavorable intermediate-risk (UIR) and high-risk (HR) prostate cancer (PCa) patients. Patients and ...
CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer. Cancer Res. 73, 2782–2794 (2013). Article CAS PubMed PubMed Central Google Scholar Wang, S. C., Yu, C. F., Hong, J. H., Tsai, C. S. & Chiang, C. ...
Remaining tissues: adrenals, extrathoracic region, gallbladder, heart, kidneys, lymphatic nodes, muscle, oral mucosa, pancreas, prostate (♂), small intestine, spleen, thymus, uterus/cervix (♀). The effective dose as computed from the above relation is good for any single tissue or organ and...
Hormone therapy, also called hormone treatment or hormonal therapy, which treats cancers that use hormones to grow (such asbreast cancerandprostate cancer). Stem cell transplants. Doctors use chemo or radiation to destroy as many cancer cells as possible, then try to replace them with healthy st...
Despite recent advances in the planning of radiation treatment and the delivery of image-guided radiation therapy, acute toxicity and potential long-term side effects often limit the ability to deliver a sufficient dose of radiation to control tumours locally. In the past two decades, a better ...