Twenty-two patients had complications considered to be delayed side effects of radiotherapy. Two patients had visual deterioration developing 3 and 6 years after treatment; six had pituitary dysfunction; and 17 had varying degrees of parenchymal changes of the brain, occurring mostly in the temporal ...
Brain injury is another severe and common side effect of IR; as many as 50–90% of patients receiving radiotherapy for brain tumors experience disabling cognitive impairment [90]. Ferroptosis has been proposed as one mechanism of neuron injury in response to irradiation and has been observed in ...
However, with a greater reliance on radiation-based methods of treatment, the incidence of radiation-induced side effects, specifically radiation necrosis, is also increasing. As a disease entity in its own right, one of the most challenging aspects of radiation necrosis lies in its diagnosis. ...
their clinical utility for radiotherapy has been less extensively explored. However, brain tumor radiotherapy is well-suited to benefit from both solid and
Though side effects from brain radiation vary, fatigue and hair loss are the most reported. However, most patients find they can continue their regular activities throughout treatment. Improved safety. A common misconception when patients hear the word radiation is that radiation will cause cancer. ...
Radiotherapy and chemotherapy are used to treat the most common malignant brain tumor in children—a medulloblastoma. The reduced volume of the hippocampus is likely due, in part, to radiation's impact on the development of new cells in the nervous system, including the growth of new neurons in...
Radiation Therapyor Radiotherapy is the delivery of high intensity X-rays, generally used in the treatment of cancers and brain disorders. There are many ways to haveradiation therapy, but they all work in a similar way. Carefully controlled high-energyX-rayskill or damagecancercells. This stops...
Targeted drugs have augmented the cancer treatment armamentarium. Based on the molecular specificity, it was initially believed that these drugs had significantly less side effects. However, currently it is accepted that all of these agents have their sp
Sherry Soeder, a certified nurse practitioner in the radiation oncology department at Cleveland Clinic, describes short-termside effectsa brain-tumor patient with a low-grade malignancy might expect, like headaches. "Patients may develop side effects specific to the location of the tumor in the brai...
The classical framework for discussing early and late side effects was the target-cell hypothesis: that the severity of side effects mainly reflected cell depletion as a result of the direct cell killing of a putative target cell leading to subsequent functional deficiency. This was the prevailing ...