A single acute dose or an accumulated acute level of radiation over a short time causes death, whereas one-tenth the lethal dose, repeated 10 times, does not cause death. In contrast, the chronic radiation effect of cancer seems to follow a different dose–response curve. For those dosed ...
They found that after lethal dose irradiation, the intestinal epithelial barrier of mice was destroyed, and the mortality rate was 100% within 15 days after radiation. Subcutaneous injection of BCN057 rescues ISCs, promotes intestinal epithelial regeneration, reduces intestinal injury, and improves the...
the surface of Mars is exposed to much higher levels of radiation than Earth. And in addition to regular exposure to cosmic rays and solar wind, it receives occasional lethal blasts that occur with strong
Without research on the impact of near-field 5G, this global step is an experiment at the population level. Bearing this in mind, there is a vital and urgent need for targeted research and for a re-evaluation of the scientific relevance of the current RF human exposure standards’ basic ...
lead shields are in place) and are generally imaged at intervals during the treatment regime that may last for weeks. Thus, it is important to insure that proper targeted tissue and only that tissue is exposed to the high level radiation because the levels of radiation are borderline lethal. ...
would have irradiated them with a lethal dose in less than 10 hours. It is also known that, during solar flares, X radiation—band 1.0-8.0 Angstrom—can reach the flux of 10−3W/m2, while in the absence of solar flares, its value is around 10−7W/m2—NASA, http://science.nasa...
All these observations are consistent with studies decades ago, in which MKs are found to be resistant to even lethal IR and to be functional in rodents for at least 7–10 d after IR [32, 33]. Mechanistically, the radiosensitivity is determined by the dynamic reprogramming of the Bcl-xL-...
Proteomics and secreted lipidomics of mouse-derived bone marrow cells exposed to a lethal level of ionizing radiationHigh doses of ionizing radiation (IR) exposure can lead to the development of severe acute radiation syndrome with bone marrow failure. Defining risk factors that predict adverse ...
“+4” position cells are low-proliferative under homeostasis, while become proliferative from 3–4 days after high-dose radiation15,16. However, during lethal IR exposure, the CBCs are exhausted rapidly and the intestinal epithelium always disintegrates around 5 days after radiation, which happens...
To address whetherNlrp3knock out can overcome the lethal effect of radiation, a group of 9.5 Gy radiatedNlrp3−/−mice (Nlrp3−/−+9.5 Gy,n=22) were monitored for 30 days in comparison with a group of 9.5 Gy radiated WT mice (WT+9.5 Gy,n=25).Nlrp3−/−kn...