(S27-2) Endothelial apoptosis is the primary lesion initiating radiation damage to the intestines .Fuks, ZviParis F, Fuks Z, Kang A, Capodieci P, Juan G, Ehleiter D, Haimovitz-Friedman A, Cordon-Cardo C, Kolesnick R. Endothelial apoptosis as the primary lesion initiating radiation damage...
Concurrently excessive disintegration of crypt cells in the intestines was observed. The intestinal damage is considered to be the result of a cytotoxic action of the antibody-producing foreign lymphoid cells against the intestinal crypt cells. The intestinal lesons resemble those found in irradiated ...
Excessive inflammation will also lead to damage to the body [24]. The main mechanism of ferroptosis is that, under the action of bivalent iron or ester oxidase, it catalyzes the highly expressed unsaturated fatty acids on the cell membrane and causes lipid peroxidation, thus inducing cell death...
we've heard more about the potential health benefits of so-called probiotics. And now Washington University researchers have found that one probiotic appears to protect the small intestine from radiation damage. Intestinal damage can be a problem for patients receiving radiation therapy for abdominal c...
Interestingly, Wnt3a and active β-catenin protein levels were increased in the small intestines of MSC-treated mice. In addition, intravenous delivery of recombinant mouse Wnt3a after radiation reduced damage in the small intestine and was radioprotective, although not to the same degree as MSC ...
Radiation therapy for abdominopelvic malignancies often results in damage to the gastrointestinal tract (GIT) and permanent changes in bowel function. An o... A Jameus,J Dougherty,R Narendrula,... - 《International Journal of Molecular Sciences》 被引量: 0发表: 2024年 TECHNIQUE OF ARGON PLASM...
External irradiation—when all or a portion of the body is exposed to penetrating gamma radiation from an external source. Significant cellular damage can occur. Following exposure, the patient is not radioactive and can be managed like any other patient with no threat to staff, such as a pati...
Radiation can cause DNA damage to intestinal epithelial cells via direct or indirect means, leading to cell death and tight junction damage, which subsequently disrupt the integrity of the intestinal mechanical barrier [24]. After exposure to ionizing radiation, the main death mode of intestinal ...
Radiation to the head and neck area can damage the glands, causing throat and mouth sores. Radiation to the stomach or pelvis can damage the intestines. Radiation also limits reconstructive options for breast cancer, and can cause significant damage to the heart, lungs or any other organ nearby...
Radiation therapy is the most widely used treatment for cancer, but it causes the side effect of mucositis due to intestinal damage. We examined the protective effect of genistein in tumor-bearing mice after abdominal irradiation by evaluation of apoptosis and intestinal morphological changes. Methods...