Twenty-two patients had complications considered to be delayed side effects of radiotherapy. Two patients had visual deterioration developing 3 and 6 years after treatment; six had pituitary dysfunction; and 17 had varying degrees of parenchymal changes of the brain, occurring mostly in the temporal ...
Toxicity to central nervous system tissues is the common side effects for radiotherapy of brain tumor. The radiation toxicity has been thought to be related to the damage of cerebral endothelium. However, because of lacking a suitable high-resolution vivo model, cellular response of cerebral ...
Twenty-two patients had complications considered to be delayed side effects of radiotherapy. Two patients had visual deterioration developing 3 and 6 years after treatment; six had pituitary dysfunction; and 17 had varying degrees of parenchymal changes of the brain, occurring mostly in the temporal ...
The classical framework for discussing early and late side effects was the target-cell hypothesis: that the severity of side effects mainly reflected cell depletion as a result of the direct cell killing of a putative target cell leading to subsequent functional deficiency. This was the prevailing ...
Toxicity to central nervous system tissues is the common side effects for radiotherapy of brain tumor. The radiation toxicity has been thought to be related to the damage of cerebral endothelium. However, because of lacking a suitable high-resolutionmodel, cellular response of cerebral capillaries to...
Radiotherapy and chemotherapy are used to treat the most common malignant brain tumor in children—a medulloblastoma. The reduced volume of the hippocampus is likely due, in part, to radiation's impact on the development of new cells in the nervous system, including the growth of new neurons in...
What Are the Late Side Effects From Radiation Therapy? Late side effects from radiation therapy take months and sometimes years to show up and usually don’t go away. But not everyone will have them. These problems happen when radiation damages your body. For example, scar tissue can affect ...
Brain Brain injury is another severe and common side effect of IR; as many as 50–90% of patients receiving radiotherapy for brain tumors experience disabling cognitive impairment [90]. Ferroptosis has been proposed as one mechanism of neuron injury in response to irradiation and has been observed...
"We wanted to see what the quantitative benefits of such a new protocol would be," says Papp. "How much can you reduce the radiation's effect on the liver while making sure that the tumor receives a consistent and effective dose? A reduction of 20 percent would reduce side effects enough...
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