This paper summarizes current knowledge on ionizing radiation-associated breast cancer in the context of established breast cancer risk factors, the radiation dose–response relationship, and modifiers of dose response, taking into account epidemiological studies and animal experiments. Available ...
To evaluate this risk, Kirova et al. conducted a retrospective review of the records of 16,705 patients treated for nonmetastatic breast cancer (median age 55 years) who were prospectively registered in a French breast cancer database. In total, 13,472 (80.6%) patients had received RT and ...
CONCLUSIONS: Heterozygous carriers of loss of function mutations in ATM that are A-T causing, are at increased risk of breast cancer. However, examination of a range of genetic variants, both rare and common, across multiple cancers, suggests that ATM may have additional effects on cancer risk...
This paper summarizes current knowledge on ionizing radiation-associated breast cancer in the context of established breast cancer risk factors, the radiation dose–response relationship, and modifiers of dose response, taking into account epidemiological studies and animal experiments. Available epidemiological...
Breast cancer survivors have an increased risk of hypothyroidism.Radiation therapy to the supraclavicular lymph nodes further increases this risk.The thyroid gland may be an organ at risk in breast cancer patients.Using volume-based delineation may spare the thyroid gland from radiation damage.关键词:...
Therefore, it is advised that clinicians perform a breast cancer risk analysis in order to raise awareness and establish dose optimization protocols. The objective of this work is to assess the effective and breast equivalent doses during PET)/CTimaging examinations....
431 Diagnostic radiation exposure and risk of breast cancer in BRCA1/2 mutation carriers in the GENE-RAD-RISK study: a report from the GENEPSO, EMBRACE, and HEBON Collaborators groupPijpeA.AndrieuN.EastonD.F.KesminieneCardisE.ingentaconnectEuropean Journal of Cancer Supplement...
Breast cancer and breast cancer-directed radiation therapy (RT) may increase the risk of late effects, such as hypothyroidism. We conducted a systematic review and meta-analysis to investigate the association between breast cancer, RT, and risk of hypothyroidism in breast cancer survivors. Methods ...
Both frequency and type of breast cancer are affected by prior radiation exposure. Many epidemiological studies suggest that radiation risk is inversely related to age at exposure; exposure during puberty poses the greatest risk while exposures past the menopause appear to carry very low risk. These...
In recent years, breast cancer-related lymphedema (BCRL), which affects one in five patients treated for breast cancer (BC), has garnered increasing interest by clinicians and researchers as BC survival rates improve and survivorship issues become increasingly imperative. This review represents an ov...