Radiation therapy is a standard therapeutic option in the post-operative setting for early breast cancer patients after breast conserving surgery, providing a substantial benefit in reducing the risk of local relapse with a consequent survival gain. Nevertheless, the reduction in the burden related to...
Major prospective phase 3 trials investigating the benefit of adjuvant radiation therapy after breast-conserving surgery for DCIS are summarized in Table 5 (Fisher et al., 1998, 1999; Houghton et al., 2003; Breast Cancer Cooperative Group et al., 2006; Emdin et al., 2006; McCormick et al....
CHICAGO, June 4 (Xinhua) -- The presence of cancer cells in the blood of patients with early-stage breast cancer may be predictive of a benefit from radiotherapy delivered after surgery, according to a study posted on the website of Northwestern University (NU). The researchers analyzed data ...
Radiotherapy (RT) is an effective treatment for managing breast cancer patients with breast conserving surgery, but patients may experience radiation-induced shoulder problems. Even though the course of shoulder morbidity is unknown, pectoral muscle changes after radiotherapy can be a major cause of ...
Importantly, developments in the treatment of breast cancer include the increasing use of primary systemic therapy. It should be further investigated whether these results hold true when systemic therapy is not given after, but before surgery of the primary tumour. It would also be of interest to...
A cost comparison analysis of partial versus whole-breast irradiation after breast-conserving surgery for early-stage breast cancer Purpose: To assess, if and for whom, there are cost savings associated with alternate breast radiotherapy (RT) techniques when compared with the convention... WW Suh,...
co-director, Lester and Sue Smith Breast Center, co-associate director, clinical research, Dan L. Duncan Comprehensive Cancer Center, discusses ongoing challenges in determining the optimal treatment strategy for patients with early-stage breast cancer, including the necessity of surgery a...
After excluding women who did not receive RT and women who had a personal history of cardiovascular disease or heart surgery before breast cancer diagnosis, the final study size was 972 women (Figure 1). Download: Download high-res image (492KB) Download: Download full-size image Figure 1. ...
We measured patient satisfaction regarding breast cancer treatment by using a continuous percentage (full satisfaction = 100%; no satisfaction = 0%) for the overall treatment and for each specific treatment (surgery, radiation therapy). In addition, we asked questions regarding the following hypothesiz...
Early Breast Cancer Trialists' Collaborative Group et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet 378, 1707–1716 (2011). Yang, J. C...