( 2008 ) Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp . Cell 133 , 601 – 611 .Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Y Fu,Y Zhu,K Zhang,M Yeung,D Durocher,W Xiao. Cell . 2008...
The interaction of Rad6/Rad18 with PCNA is paramount to PCNA monoubiquitination and remains poorly defined. In particular, the location of the Rad6/Rad18 binding site on PCNA is unknown. Many PCNA-binding proteins, particularly DNA polymerases (pols), converge on PCNA encircling stalled P/T ...
pCMV-SPORT6-RAD18(cattle) 市场价:¥872.00 商城价:¥697.60 100% 好评率 1 累计销量 满200包邮:消费满200元包邮商品品牌: 索莱宝 包装规格: 1株商品运费: 运费10元 商品数量: (库存5)立即购买 加入购物车 咨询 收藏 举报---看了又看--- pCMV-SPORT6-...
Rad6/Rad18 competes with DNA polymerases η and δ for PCNA encircling DNA family (pol 畏) and a B-family (pol 未) pol critical to TLS each inhibit transfer of ubiquitin from Rad6/Rad18 to PCNA and; 2) the observed inhibitions are dependent on the interaction of these pols with PCNA...
pCMV-SPORT6-RAD18(1点突变)人源基因质粒 基本信息: 别名:NM_020165.3;RNF73 质粒分类: 复制子:pUC 质粒宿主:大肠杆菌 质粒用途:基因模板 片段类型:ORF 克隆菌株:DH* 片段物种:人 原核抗性:Spe 培养条件:37度 本产
To further examine Poleta functions and the mechanisms that regulate this important protein, Poleta complexes were purified from HeLa cells over-expressing epitope-tagged Poleta, and polypeptides associated with Poleta, including Rad18, Rad6 and Rev1, were identified by a combination of mass ...
9-1-1 clamp ubiquitylation and the DNA-damage response are mutually independent Ubiquitylation of the 9-1-1 subunit Rad17 is independent of lysine 197, Rad6, and Rad18 Lysine 197 does not contribute to Rad17 function in checkpoint activation Rad17 ubiquitylation can cause proteasomal degradation...
CAS号 781676-86-6 分子式 C65H106O31 产品名称 两头尖皂苷R18 产品类型 标准品 产品规格 5 mg 有效成分含量 98% 是否进口 否 用途范围 本品用于大学实验室、科研院所、制药企业科研部门实验室含量测定、鉴别、药理实验、活性筛选本品用于大学实验室、科研院所、制药企业科研部门实验室含量测定、鉴别、...
2101739-18-6.mol 化学性质安全信息用途价格供应商25 RAD51-IN-17化学性质 沸点: 569.9±60.0 °C(Predicted) 密度: 1.24±0.1 g/cm3(Predicted) 储存条件: Store at -20°C 溶解度: DMSO : 62.5 mg/mL (167.19 mM; Need ultrasonic) 形态:
Here, we analyze the NBS1-deficient cells and show that NBS1 interacts with RAD18 through a RAD6-like domain near the C terminus of NBS1 and recruits RAD18 to UV-induced DNA damage. The similarity between the RAD18-binding domain of NBS1 and RAD6 reveals a protein-protein interaction ...