The non-enzymatic dithiol-disulfide reaction leads to synergistic reduction of the enantiomers which can explain the higher antioxidant activity of racemic lipoic acid found in vivo (Maitra et al. Biochem. Biophys. Res. Commun. 221:422–429, 1996) in comparison to the enantiomers. Lipoic acid...
The non-enzymatic dithiol-disulfide reaction leads to synergistic reduction of the enantiomers which can explain the higher antioxidant activity of racemic lipoic acid found in vivo (Maitra et al. Biochem. Biophys. Res. Commun. 221:422–429, 1996) in comparison to the enantiomers. Lipoic acid...
The non-enzymatic dithiol-disulfide reaction leads to synergistic reduction of the enan- tiomers which can explain the higher antioxidant activity of racemic lipoic acid found in vivo (Maitra et al. Biochem. Biophys. Res. Commun. 221:422-429, 1996) in comparison to the enantiomers. Lipoic ...
Fried H,Balkeenhohl,Joachim P,et al.A short and productive syn-thesis of racemicα-lipoic acid. Zeitschrift fur Naturforschung . 1999FRIEDHELM BALKENHOHL, JLACHIM PAUST, et al. A short and productive synthesis of racemic α-Lipoic Acid [J]. Z Naturforsch, 1999, 54: 649-654....
Fried H,Balkeenhohl,Joachim P,et al.A short and productive syn-thesis of racemicα-lipoic acid. Zeitschrift fur Naturforschung . 1999FRIEDHELM BALKENHOHL, JLACHIM PAUST, et al. A short and productive synthesis of racemic α-Lipoic Acid [J]. Z Naturforsch, 1999, 54: 649-654....
Compound (II) was thionated earlier with an alcoholic solution of sodium disulfide , obtained from sodium sulfide and sulfur. At the end of the thlonation reaction the alcohol was distilled in vacuum and (III) was extracted from the residue with chloroform. The chloroform extracts were ...
(57)< Abstract > As for this invention, the racemic body or the enantiomer of the lipoic acid of restoration type or oxidation type, or the salt which on that medicine is admitted, amide, it regards ester or thio ester the use as the active ingredient in the prevention or short-term ...
The invention relates to the use of racemic a-lipoic acid or its enantiomers or pharmaceutically acceptable salts, amides, esters or thioesters thereof, in reduced or oxidized form, as active ingredient in the prevention or the acute or chronic treatment of migraine.PEUKERT MANFRED...
1996. Enantioselective pharmacokinetics and bioavailability of different racemic α-lipoic acid formulations in healthy volunteers. Eur. J. Pharm. Sci. 4 : 167-174 CrossRef .R. Hermann , G. Niebch, H.O. Borbe, Enantioselective pharmacokinetics and bioavailability of different racemic alpha-lipoic ...
Koteshwar, "Remote control of stereoselectivity: Lipase catalyzed enantioselective esterification of racemic α-lipoic acid", Tetrahedron Asym., 1997, 8, 337-339.Fadnavis, N. W.; Koteshwar, K. Remote control of stereo- selectivity: lipase catalyzed enantioselective esterification of racemic lipoic acid...