Fast resolutions of racemic compounds (sulfoxides, amino alcohols, and α-methylarylacetic acids derivatives) were achieved on a chiral microbore column using carbon dioxide and a polar methanol/dioxane modifier. The stationary phase used in this study contains the 3,5-dinitrobenzoyl derivative of ...
s (50:50) of both enantiomers of an asymmetric chemical compound (e.g., ofl- andd-alanine); by definition its enantiomeric excess equals zero; it induces no rotation of polarized light. The term racemic should not be confused with the termachiral, which does not include chiral compounds....
Optically active compounds of this type, (S)-9f (ee 99%) and (R)-9f (ee 92%). were obtained by semi-preparative chiral HPLC. The optically active arenesulfonimidoyl imidazolium salt (R S,R C-)-8j was prepared by diastereoselective methylation (de > 90%) of the optically pure ...
From racemic compounds through metastable to stable racemic conglomerates: crystallization features of chiral halogen and cyano monosubstituted phenyl glycerol ... AA Bredikhin,ZA Bredikhina,FS Akhatova,... - 《Tetrahedron Asymmetry》 被引量: 12发表: 2009年 From racemic compounds through metastable ...
Although the number of organic compounds forming conglomerate systems is not large, a significant number of other chiral compounds can be transformed into conglomerate-forming systems through formation of a salt or covalent derivative. For example, substitution of additional functionalities onto the achiral...
A series of phosphinyl-, phosphonyl- and phosphorylacetates was hydrolyzed in the presence of Pig Liver Esterase (PLE) to give the corresponding P-chiral phosphoroacetic acids and unreacted esters in a high enantiomeric purity (up to 100% ee).doi:10.1080/10426509608545199...
Simon H, Bader J, Gunther A, Neumann S, Thanes J (1985) Chiral compounds synthesized by biocatalytic reduction. Angew Chem Int Ed Engl 24:539–553 Google Scholar Sit SY, Parker RA, Motoe I, Han W, Balasubramanian H, Cott JD, Brown PJ, Harte WE, Thompson MD, Wright JJ (1990) Syn...
Here, we showed how a chiral reagent reacts with a racemic mixture to lead to compounds with non-isomeric structures based on which enantiomer is incorporated in the final product. This type of structural divergence based on supramolecular interactions could be the seed that led to the demise ...
GENERATION of optical activity in a racemic mixture of enantiomers, a process relevant to the origin of life and of naturally chiral compounds 1 , requires chirality in the interaction responsible for the transformation or the environment in which it occurs. Without violating this strict requirement,...
Even though the ground-state distribution of a mixture of chiral molecules is racemic, in some cases it is still possible to measure the CPL if the excited state can be enriched in one of the enantiomers. If, for example, the excitation beam is circularly polarized, one of the enantiomers ...