Such viruses could form the basis of future vaccines for rabies (reviewed by Hicks et al[41]) and one variant has been trialled as an oral vaccine for wildlife[42]. The method of attenuation falls into two categories. The first are those constructs that have a gene deletion, usually the...
I was immediately rushed to get Abhyarab, a tetanus vaccine and injected with Immunoglobin. After four days I got a mild fever with tiredness, and also started salivating more, and for a moment I had difficulty breathing. Has the rabies viruses been transmitted to me? I have developed fear...
Additionally, the lengthy campaign time lowered population immunity through high population turnover and the short life of the vaccine that was used [9, 10]. In late 2010, a local non-governmental organization (NGO), the Bali Animal Welfare Association (BAWA), togethe...
results suggest possible multiple introductions of rabies into the Middle East, and regular trans-boundary movement of disease. Although 4000 years have passed since the original description of disease consistent with rabies, animals and humans are still dying of this preventable and neglected zoonosis....
Animal studies have demonstrated that rabies-specific antibodies, especially the neutralizing antibodies, played an essential role in vaccine-mediated protection6. Yet, clinical evaluation of rabies vaccines in humans is not possible due to ethical considerations. Therefore, new rabies vaccines or rabies-...
Predicted results from OLS regressions of the number of dogs vaccinated by vaccinator per hour, for (A) all vaccination strategies combined, (B) mobile static point (MSP), (C), MSP + capture vaccinate release (CVR), and (D) door-to-door vaccination (DDV) and oral rabies vaccine ...
as Pasteur used a neurotropic agent in his vaccine, there could be no guarantee that the paralyzing and neurological effects were not just a cause of the vaccine itself. There were more cases of paralytic rabies due to Pasteur’s vaccination than in “natural” rabies for which it was rare...
Vaccine. 1996, 14 (3): 185-186. 10.1016/0264-410X(95)00197-9. Article CAS PubMed Google Scholar Haydon DT, Randall DA, Matthews L, Knobel DL, Tallents LA, Gravenor MB, Williams SD, Pollinger JP, Cleaveland S, Woolhouse MEJ, et al: Low-coverage vaccination strategies for the ...
Bakker AB, Python C, Kissling CJ, Pandya P, Marissen WE, Brink MF et al (2008) First administration to humans of a monoclonal antibody cocktail against rabies virus: safety, tolerability, and neutralizing activity. Vaccine 26(47):5922–5927 Article CAS PubMed Google Scholar Bakker KM, Rocke...
Nagarajan T, Rupprecht CE, Dessain SK et al (2008) Human monoclonal antibody and vaccine approaches to prevent human rabies. In: Dessain SK (ed) Human antibody therapeutics for viral disease. Current topics in microbiology and immunology, vol 317. Springer, Berlin, Heidelberg. https://doi.org...