Modifications were made to the language of the guidelines to clarify the recommendations and better specify the situations in which rabies post- and pre-exposure prophylaxis should be administered. No new rabies biologics are presented, and no changes were made to the vaccinat...
In the absence of pre- or post-exposure prophylaxis, rabies is the only known virus with a 100% case fatality rate once clinical symptoms are observed [14]. There are two inactivated rabies vaccines currently licensed for human use in the United Kingdom (UK). The first is Rabies vaccine ...
Although traditional inactivated RABV vaccines have been used for pre- and post-exposure prophylaxis in humans with high safety and efficacy, they are not useful for delayed treatment and can even accelerate the rabies (CDC, 2010; Rupprecht et al., 2002; Sampath et al., 2005). Other vaccines...
Immunogenicity and 1-year boostability of a three-dose intramuscular rabies pre-exposure prophylaxis schedule in adults receiving immunosuppressive monotherapy: a prospective single-centre clinical trial Article 作者:Goorhuis, Abraham;van Gucht, Steven;van Put, Bridget;Grobusch, Martin P;Spuls, Phyllis...
more than 2.5 billion people are at risk in over 100 countries reporting the disease. Rabies has the tenth highest mortality of all infectious diseases worldwide. There are still about 50000 to 60000 human deaths annually although effective vaccines for post-exposure treatment are available [12]. ...
Risk of rabies transmission and adverse effects of postexposure prophylaxis in health care workers exposed to a fatal case of human rabies On May 27, 2008, a patient died from rabies at the Cayenne Hospital in French Guiana. Postexposure prophylaxis vaccination was implemented for all health c....
An important public health problem: rabies suspected bites and post-exposure prophylaxis in a health district in Turkey The aim of this study was to describe rabies suspected animal bites and post-exposure prophylaxis (PEP) practices in Narlidere District in Turkey between 1... B Kilic,B Unal,...
Rabies DNA vaccine encoding lysosome-targeted glycoprotein supplemented with Emulsigen-D confers complete protection in preexposure and postexposure studies in BALB/c mice. FASEB J. 2010 Jan;24(1):173-83. Epub 2009 Sep 9.Kaur M, Saxena A, Rai A, Bhatnagar R. Rabies DNA vaccine encoding...
Recent studies suggest that human diploid cell rabies vaccine (HDCV) may not always produce acceptable titers after intradermal (id) preexposure prophylaxis. To simulate accidental deviation from the recommended route of administration and to determine the immunogenicity of smaller-than-recommended doses...
The purpose of this study is thus first to characterize the current trends of human rabies in China from 1990 to 2007, and then to define better recommendations for improving the post-exposure prophylaxis (PEP) schedules delivered to rabies patients. Methods:The most updated epidemiological data ...