Open sesame--treating rabies in the brainDavid Ojcius
Evaluation of efficacy of anti-rabies virus drug (small molecular weight compound) against lethal rabies virus infection in a BALB/c mouse modelMice Short-term and one-year duration of immunity field efficacy of the killed rabies vaccine (Defensor 3), against USDA rabies challenge virus (New Yor...
Distribution of RABV-infected cells in the brain after peripheral infection It has been reported that the mice infected with street strains showed a relatively limited distribution of the virus in the brain compared to the CVS strain5. To compare the extent of virus distribution in the brain afte...
healing saint, is depicted with a large key that was heated and used for cautery. In the twelfth century, Maimonides advised thoroughwoundcleansing, suction, cautery, and rest. Wound cautery remained part of most suggestions for potentially rabid animal bites into the middle of the 20th century....
A complete source for information on rabies and rabies exposure in the US including tools and resources.
Registerorlog in, in order to read the full article. Pathophysiology Rabies virusbinds theAChreceptorofperipheral nervesin the bite wound → migratesretrogradelyalong the axonalmicrotubules(using motor proteindynein) → enters theCNS→ infects the brain ...
Rabies is a deadly disease that attacks the brain and nervous system of mammals. Protect your pet from rabies with an up-to-date vaccination from your veterinarian.
The rabies virus infects the central nervous system of mammals, ultimately causing disease in the brain and death. Infection causes tens of thousands of deaths every year, mainly in Asia and Africa. Approximately 40% of people bitten by suspect rabid animals are children under 15 years of age...
For example: electrical messages move from nerve cells located in the brain, down an axon to the spinal cord. Chemical messages cross from the end of that 'brain-derived' axon to the nerve cell of the target spinal cord nerve (whose own axon and nerve-ending supplies the muscles that the...
However, measles virus can reach the brain and cause measles inclusion-body encephalitis, and in infants infected in the first 2 years of life, the virus can persist in the brain and cause a disease called subacute sclerosing panencephalitis when children reach school age; they show behavioral ...