In rabies-free countries, cases reported in domestic animals are the result of the importing of pets from areas where canine rabies isendemic. Thesylvatic cycleis predominant in the northern hemisphere. In Europe, probably due tospilloverfrom domestic animals during the Second World War,the main ...
Rabies is a life-threatening neglected tropical disease: tens of thousands of cases are reported annually in endemic countries (mainly in Africa and Asia), although the actual numbers are most likely underestimated. Rabies is a zoonotic disease that is caused by infection with viruses of the Lyssa...
Most deaths from rabies in the United States and Canada result from bat bites; the most recent fatality was a 66-year-old man in California who died in September 2003. The death of a nine-year-old girl in Quebec in the fall of 2000 was the first case of human rabies in Canada since...
Rabies remains a major public health problem in low- and middle-income countries. However, human rabies deaths are rarely laboratory-confirmed or sequenced, especially in Africa. Five human rabies deaths from Tanzania and Kenya were investigated and the causative rabies viruses sequenced, with the ai...
Rabies still causes more than 70,000 deaths a year, half of them in children, and remains a severe threat for humans. The next important challenges would be the oral vaccination of stray dogs and pre-exposure vaccination of young individuals in endemic countries....
Key Points Rabies is an acute, progressive, incurable viral encephalitis. This zoonosis has the highest case fatality of any infectious disease. All mammals are believed susceptible to rabies virus and other lyssaviruses. Dog vaccination is the single most useful and cost-effective measure for moder...
Rabies is the oldest diseases known to mankind. Occurring on all continents, except Antarctica, rabies remains one of the neglected tropical diseases (NTD) that predominantly affects the poor of the poor particularly in Asia and Africa still causing tens
A few countries claim to be free of the disease because of either successful elimination programs or thanks to island status and enforcement of rigorous quarantine regulations. Rabies emergence may be affected by changes in virus-host dynamics or human translocation of infected species. For many ...
(Wildeet al., 2005). Rabies is emerging again in China, which was virtually rabies-free during the reign of Mao Zedong. Japan, Taiwan, Malaysia, Singapore, and South Korea eliminated canine rabies decades ago. No other Asian countries have succeeded in doing so. Rabies can also be ...
This article describes experiments indicating a change in pathogenicity for laboratory animals of the Flury strain of rabies virus at high egg passages. Factors such as dilution of virus, number of egg passages, age of animals, and route of inoculation are taken into account. The results of the...