R2G2 mice show dose dependent effects of oestrogen on morbidity. These data will allow researchers to determine the optimal dose for use in the R2G2 model. Conclusion In conclusion, these data support that the R2G2 mouse model may be a good alternative to SCID models when administering DNA damaging chemother...
Primary cortical neurons in cultures established from embryonic day 15 SOD2+/+ and SOD2-/- mice appear similar during the first 24h in culture. During the ensuing two days in culture, SOD2-/- neurons exhibit a profound reduction of neurite outgrowth and their mitochondria become fragmented and...
Head and neck PDX 626 and 635 was transplanted in into 4 sections of R2G2 mice each, and 100% of mice developed either one or two tumours. The human esophageal adenocarcinoma OE33 cells were implanted into both flanks of R2G2, Athymic Nude and SCID mice. There was a 100% take rate ...