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12. Skene,P. J., Henikoff, J. G. & Henikoff, S. Targeted in situ genome-wideprofiling with high efficiency for low cell numbers.Nat Protoc13,1006-1019, doi:10.1038/nprot.2018.015 (2018). 13. Skene,P. J. & Henikoff, S. An...
12. Skene,P. J., Henikoff, J. G. & Henikoff, S. Targeted in situ genome-wideprofiling with high efficiency for low cell numbers. Nat Protoc 13,1006-1019, doi:10.1038/nprot.2018.015 (2018). 13. Skene,P. J. & Henikoff, S. An efficient targeted nuclease strategy forhigh-resolution map...
近日,中国农业科学院深圳农业基因组研究所(岭南现代农业科学与技术广东省实验室深圳分中心)徐炜团队开发了一项高通量、低成本R-loop定量图谱绘制技术“mDRIP-seq”,并应用该技术绘制了酿酒酵母突变株R-loop定量图谱。该研究成果以“mDRIP-s...
The R-loop profiling of gDNA from ∼500,000 muscle cells was performed by basic ssDRIP-seq as the positive control. The sequencing results, presented by Pearson's correlation coefficient, showed high positive correlations between ssDRIP-seq and ULI-ssDRIP-seq, while a low correlation was ...
and methods of R-loop profiling,reviewing recent research advances on R-loops in plants.Furthermore,we provide perspectives on future research directions for R-loop biology in plants,which might lead to a more comprehensive understanding of R-loop functions in plant genome regulation and contribute ...
Genome-wide profiling of circular RNAs, alternative splicing, and R-loops in stem-differentiating xylem of Populus trichocarpa. J Integr Plant Biol, 2021, 63: 1294–1308 56 Xu C, Wu Z, Duan H C, et al. R-loop resolution promotes co-transcriptional chromatin silencing. Nat Commun, 2021, ...
Fig. 1: Identification and genome-wide profiling of the SOSS–INTAC complex. a, Mass spectrometry analyses of endogenous INTS3 and SSB1 IP using nuclear extracts. The values are intensity-based absolute quantification intensities for SOSS, INTAC and Pol II subunits. IgG was used as the bindi...