其二,“免疫+”模式的深入探索。免疫+化疗的持续优化,以及免疫+化疗+靶向治疗,包括与靶向VEGFR、FGFR、PDGFR和c-kit等多个靶点的抗血管生成药物或与SCLC特定分子靶向药物联合应用,有望进一步提升ES-SCLC疗效。同时,免疫+放疗具有协同作用,...
寻找一种更有效的靶向药物以延长RAIR-DTC患者的生存,进一步改善其预后成为当时研究的重点之一。仑伐替尼作为RTK抑制剂,不仅可抑制VEGFR1-3和FGFR1-4通路,还可抑制血小板源性生长因子受体(PDGFR)、转染期间重排(RET)激酶及c-KIT等多种通...
5159 (Human); 18596 (Mouse); 24629 (Rat) Alternate Names beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140b antigen; CD140b; EC 2.7.10; EC 2.7.10.1; JTK12; PDGF R beta; PDGFR; PDGFR1; PDGFRB; PDGF-R-beta; platelet-derived growth factor ...
5156 (Human); 18595 (Mouse) Alternate Names alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PDGF-R-alpha; platelet-derived...
Sorafenib (Bay 43-9006) 是一种多激酶抑制剂,抑制 Raf-1、B-Raf、VEGFR2、VEGFR3、VEGFR4、PDGFRβ、FLT3、c-Kit 等 (IC50=6/22/90/15/20/20/57/58 nM),具有口服活性。Sorafenib 具有抗肿瘤活性,可以诱导细胞自噬和凋亡,也可以激动铁死亡。
鬼臼毒素(5毫克)产品是A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC₅₀ ~ 1 nM. Displays an
PDGF-B PDGF-C PDGF-D PDGF-R PDGF-R-alpha PDGF-R-beta PDGF1 PDGF2 PDGFA PDGFA PDGFA-Associated Protein 1 PDGFB PDGFB PDGFB PDGFC PDGFC PDGFD PDGFD PDGFR PDGFR PDGFR-1 PDGFR-2 PDGFR-alpha PDGFR-beta PDGFR1 PDGFR2 PDGFRA PDGFRA PDGFRA/BCR fusion PDGFRB PDGFRB PDGFRL PDGG PDGI ▼Co...
View Human Phospho-PDGF R beta (Y1021) Antibody (AF2316) validated in Human & Western Blot from R&D Systems.
另外达沙替尼拥有BCR-ABL、SRC家族(SRC、LCK、YES、FYN)、c-KIT、EPHA2、PDGFR-β等众多靶点，可能...
ApoptosisAutophagyc-KitFerroptosisFLTPDGFRRafVEGFR ¥ 153 现货 规格 数量 客户已引用 α-Vitamin E 天然维生素E, Vitamin E, D-α-Tocopherol, Alpha-Tocopherol, 5,7,8-Trimethyltocol, (+)-alpha-Tocopherol T164859-02-9 α-Vitamin E (Dexrabeprazole Sodium) 是一种天然存在的维生素 E,也是抗氧化剂。