G quartets may regulate the translation of the mRNA transcript of Fragile X gene and thus, control synaptic activity of neurons in the brain. Despite the presence of well-defined non-guanine base quartets in a number of NMR and X-ray structures, the data suggests that most non-guanine ...
The structure of a complex between heme(Fe(3+)) and a parallel G-quadruplex DNA formed from a single repeat sequence of the human telomere, d(TTAGGG), has been characterized by (1)H NMR. The study demonstrated that the heme(Fe(3+)) is sandwiched between the 3'-terminal G-quartets of...
Data from powder XRD, 1H double-quantum solid-state magic-angle spinning (MAS) NMR and small-angle neutron scattering (SANS) were consistent with a structural model that involves formation of borate dimers and G4·K+ quartets by G 1 and KB(OH)4. Stacking of these G4·M+ quartets into ...
(2004) G-quartets 40 years later: from 5’-GMP to molecular biology and supramolecular chemistry. Angew. Chem. Int. Ed. 43, 668–698. CrossRef Chen, F. M. (1992) Sr2+ facilitates intermolecular G-quadruplex formation of telomeric sequences. Biochemistry, 21, 3769–3776. CrossRef ...
Specific stacking interactions amongst two G‐quartets flanking base triples and base pairs in TD and KDH+ forms are reflected in 10?K higher thermal stability of KDH+. Populations of TD and KDH+ forms are controlled by pH. The (de)protonation of A20 is the key for pH driven structural ...
Specific stacking interactions amongst two G‐quartets flanking base triples and base pairs in TD and KDH+ forms are reflected in 10?K higher thermal stability of KDH+. Populations of TD and KDH+ forms are controlled by pH. The (de)protonation of A20 is the key for pH driven structural ...
Synthesis and structure of six-coordinated organobismuth compounds with bidentate ligands (12Bi6) The thermally stable 12-Bi-6 compound 3-Li+, {(o-C6H4C(CF3)20)2}Bi(p-CH3C6H4)2-Li+, was synthesized. F-19 NMR of 3-Li+ showed a pair of quartets at room temperature but showed a ...
Quartets MaxCut: A Divide and Conquer Quartets Algorithm The recursion for unrooted quartets, however, is more complicated in that even with completely consistent set of quartet trees the problem is NP-hard, as... S Snir,S Rao - 《IEEE/ACM Transactions on Computational Biology & Bioinformatics...
NMR study on cation binding between G-quartets in tetramolecular G-quadruplex adopted by d(5′TGG3′–3′GGT5′) with 3′–3′ inversion of polarity sites in the middle of G-tract showed existence of two different G-quadruplex forms with all strands in parallel orientation, where all ...
ff., J. Plavec and co‐workers show that a sequence with four GGG‐tracts folds into a G‐quadruplex with two quartets stabilized by A?G?A and G?G?G base‐triads. Modification of a single adenine modulates the loop interactions and leads to exciting structural changes including a two‐to...