In response to this need, we developed a high-throughput, robust, sensitive, accurate, and precise assay for simultaneous measurement of trace levels of eight phthalate metabolites in human urine by HPLC-MS/MS.
NMR spectra provide various types of information, usually focused on the identification of the compounds contained in a sample; however, it’s well-known that quantitative data can also be obtained. Relative quantitation: the measurement of the ratio of a target component contained within the sample...
The rapid development of purification processes for polysaccharide vaccines is constrained by a lack of analytical tools current technologies for the measurement of polysaccharide recovery and process-related impurity clearance are complex, time-consuming, and generally not amenable to high throughput process...
www.nature.com/scientificreports OPEN Quantitative T2 MRI is predictive of neurodegeneration following organophosphate exposure in a rat model Kevin Lee1,2,3, Sara Bohnert4, Matthew Bouchard1,2,3, Cory Vair4, Jordan S. Farrell1,5, G. Campbell Teskey1, John...
and was compared with spiked sample whose concentration of the analyte was at the LLOQ in plasma or urine. Calibration standard samples in human plasma and urine were prepared for three separate batches. Intra- and inter-batch preci- sion and accuracy were evaluated by measurement of OLM and ...
Of these methods, development of and measurement of the intensities of the ninhydrin colours appears to be the most promising. It has been applied to both one- and two-dimensional, ascending and descending, chromatograms. In methods based ...
Quantitative composite testing model based on measurement uncertainty and its application for the detection of phthalate estersdoi:10.3389/fchem.2023.1191669composite testingmeasurement uncertaintyphthalates (PAEs)quantitative composite testing modeltoysTo improve the quantitative detection efficiency of chemical ...
Describes an assay developed for simultaneous measurement of trace levels of several phthalate metabolites in human urine by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Standard preparation; Preparation of samples; Results of instrumental analysis; Data analysis; Quality ...
In response to this need, we developed a simple, sensitive and reliable assay for simultaneous measurement of trace levels of three major Di(2-ethylhexyl)phthalate (DEHP) metabolites: mono-2-ethylhexyl phthalate(MEHP), mono-(2-ethyl-5-hydroxy hexyl)phthalate (MEHHP), mono-(2-ethyl-5-oxo...
Standard addition methodThis paper describes an capillary electrophoresis (CE) method used to quantify both succinic acid and levulinic acid in an industrial production process. Measurement was performed by CE with indirect UV detection, using potassium hydrogen phthalate as the UV-absorbing additive. ...