Controlling the quality of tablets: from their invention to the dissolution testHelmstdter, AxelPharmaceutical Historian
In the quality test of 2 brands of film coated tablets containing 20mg of metoprolol tartrate, their dissolution, weight variation, content uniformity, disintegration and hardness were studied. Their weight variation was 0.8 to 1.9%, content 20.1 to 20.4mg, and disintegration time less than 10.8 ...
The quality consistency evaluation of generic drugs focuses primarily on the re-evaluation of the quality of the oral solid preparations (including tablets, capsules, and granules) approved before the promulgation and implementation of the Drug Registration Administrative Measures in 2007. The evaluation ...
So, you have an idea for an app now what? 2. What Kind Of An App Do You Need? Mobile apps are compact software programs intended to run on various gadget platforms, for example, mobile phones, smart watches, and tablets. Compared to laptops and desktops, these apps are compressed in ...
The strengths of this study include the use of a large representative population-based sample with high participation rates and repeated detailed and standardized measures, as well as its longitudinal design, allowing a time sequence of various exposures and greater control for a wide range of poten...
45 EDT 2016 76 á1ñ Injections / General Requirements USP 39 — Copolymer Ratio2 — Glass Transition Point2 — Coating Adhesion to Stent Surface2 — Tissue Reaction Tests2 — Polymer Molecular Weight2 PRODUCT PERFORMANCE TEST A performance test for injection and implanted products must have the...
Packing materials are critical for stability. 2006.08.22. Pogány - Dar es Salaam */66 Special attention in assessment Compatibility of APIs with each other and with excipients. Stress stability of the final formulation. Equilibrium moisture content of granules and uncoated tablets. Control of ...
Conformia “ACE Tablets” (US) ? “Examplain” HCl Tablets (EU) ? “Sakura Tablet” (Japan) All Immediate Release Products 7 But there is a Dichotomy 1. Traditional Review Paradigm for ANDAs: For the most part highly successful for immediate release/solution products 2. However modified-...
The antifungal nanosphere-loaded gel drug delivery system was analyzed for in vitro drug release and ex vivo nail permeation in comparison with a control TBH gel, to investigate its capability of achieving the desired controlled drug delivery. The obtained results support the potential of this ...
However, higher levels of airflow speed might result in films of less uniform thickness, and consequently, medium values within the selected control space are preferred. 3.3. Third Step: Film Optimization Experiment Optimization of the composition was the last step in this sequence for the ...