First, a central polytarget QC (cPT-QC) is used to monitor the primer performance of each of the EuroClonality multiplex NGS assays; second, a standardised human cell line-based DNA control is spiked into each patient DNA sample to work as a central in-tube QC and calibrator for MRD ...
Short reads and low identity reads have been mostly removed. Length N50 = 36,827 bp Identity N50 = 88.53% With Illumina read reference When an external reference is provided, Filtlong ignores the Phred quality scores and instead judges read quality using k-mer matches to the reference (a...
Nonsense-mediated mRNA decay (NMD) is one of the best characterized and most evolutionarily conserved cellular quality control mechanisms. Although NMD was first found to target one-third of mutated, disease-causing mRNAs, it is now known to also ta
Note that in the above optimization problem we use error probability function . In Example 3.1 function gives an upper bound on the error but not the real aggregation error. Since, in order to solve the optimization problem we need a functional form on the error, we have formulated the optim...
lungs as PM2.5, they still cause harmful effects. Many studies of short-term PM exposure have been based on PM10measurements. Particles smaller than 0.1μm in diameter are referred to as ultrafine. These are usually measured as a number concentration rather than a mass. There is toxicological ...
Secondly, speaking about non-2X-upsized resizing, filter has to be very short (with a base length of 5-7 taps, further multiplied by the resizing factor) or otherwise the ringing artifacts will be very strong: it is a general rule that the steeper the filter is around signal frequencies ...
Eutrema salsugineum (2n = 14), a halophyte in the family Brassicaceae, is an attractive model to study abiotic stress tolerance in plants. Two versions of E. salsugineum genomes that previously reported were based on relatively short reads; thus, t
Because of the significant R&D-investment requirements, as well as the need for equipment and operational changes, existing sites with stable or declining volumes are unlikely to make a compelling business case for distributed quality control in the short and even medium term. However...
Peroxisomal quality control Peroxisome biogenesis Fig. 1: Schematics of the peroxisome biogenesis and degradation systems. The number of peroxisomes is regulated by de novo biogenesis and the growth and division of pre-existing organelles. First, peroxisomes can be formed by the maturation of preperoxi...
A short form of the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12). Int Urogynecol J. 2003;14:164–8. Google Scholar Kelleher CJ, Cardozo LD, Khullar V, Salvatore S. A new questionnaire to assess the quality of life of urinary incontinent women. BJOG. 1997;104:...