Guideline-directed medical therapyHeart failure with reduced ejection fractionTolerabilitySequenceRenin-angiotensin aldosterone system inhibitorsBeta blockersMineralocorticoid receptor antagonistsSodium-glucose cotransporter 2 inhibitorsHu, Jiun-RueySchwann, Alexandra N....
Quadruple Therapy in Heart Failure With Reduced Ejection Fraction: Don't Back Down Michelle M. Kittleson, MD, PhD; Biykem Bozkurt, MD Disclosures January 10, 2023 1 This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Appl...
IntroductionCarcinoid heart disease most frequently involves the tricuspid or, more rarely, the pulmonary valve and presents with right heart failure as 5-HT is metabolized by the lung. Left-sided valve involvement is quite rare. We describe our experience of 3 patients presenting with heart failure...
1 The benefits of BP lowering in reducing cardiovascular events are unequivocal,2 and there is clear evidence of greater benefits for combination-based therapy compared to monotherapy.3 Furthermore, numerous studies have indicated the benefits of more rapid control of BP and have shown that this ...
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Another reason to embrace quadruple medical therapy for heart failure: medications enabling tolerance of each otherHeart failureLeft ventricular ejection fractionWorsening renal functionHeart failure hospitalizationAims Whether risk of worsening renal function (WRF) during acute heart failure (AHF) ...
In‐hospital initiation of quadruple medical therapy for heart failure: making the post‐discharge vulnerable phase far less vulnerable\ndoi:10.1002/ejhf.2382Javed ButlerUniversity of Mississippi Medical Center,Jackson,MS,USAGregg C. FonarowRonald Reagan‐UCLA Medical Center,Los Angeles,CA,USAStephen ...
Background: Hospitalization of patients with heart failure makes it possible to optimize drug therapy, considerably improving the prognosis of this serious condition. Methods: We conducted a retrospective descriptive study of patients with reduced left ventricular ejection fraction (≤ 40%) in the ...
Objectives To evaluate the feasibility, safety and efficacy of early and rapid initiation of quadruple therapy (four drugs in 4 weeks – '4×4 approach') for heart failure with reduced ejection fraction (HFrEF) patients in a real-world clinical setting. Design Prospective service evaluation study...