In this prespecified analysis of the DANFLU-1 randomized trial, high-dose influenza vaccine was associated with a reduced rate of death and hospitalization with influenza or pneumonia and this effect was consistent in participants with CVD and across cardiovascular subgroups.Figure 1:Time to event ...
This randomized clinical trial compares the effect of high-dose vs standard-dose influenza vaccine on all-cause mortality and hospitalizations due to
Previously vaccinated with influenza vaccine One or two 0.5 mL doses† If two doses, administer at least 4 weeks apart 9 years and older - One 0.5 mL dose - 2.2 Administration Fluzone Quadrivalent is clear and slightly opalescent in color. Parenteral drug products should be inspected visually...
Approval of the supplemental biologics license application for Fluarix in children as young as 6 months of age was based on one phase 3 study and two supportive studies in children aged 6 months through 35 months, the company said. GlaxoSmithKline's other quadrivalent influenza vaccine (FluLaval)...
ER = emergency room; IPTW = inverse probability of treatment weighting; QIVc = cell-based quadrivalent influenza vaccine; QIVe-SD = standard-dose egg-based quadrivalent influenza vaccine; rVE = relative vaccine effectiveness Download: Download high-res image (88KB) Download: Download full-size im...
Zoster vaccine (ZV; ZOSTAVAX®; Merck & Co., Inc., Kenilworth, NJ), is a one-dose, live attenuated VZV vaccine, that is the licensed intervention for prevention of HZ in people ≥50 years of age in the United States (US) [3], [4]. ZV enhances VZV-specific immunity and thereby ...
4 Children younger than five years of age are at high risk of developing serious flu-related complications.5 The CDC recommends everyone six months of age and older without contraindications receive an influenza vaccine annual...
The TIV was presented in 5.0 mL multidose vials containing 10 doses (0.5 ml) of vaccine. The QIV was an inactivated quadrivalent, split-virion influenza vaccine (FluLaval™ Quadrivalent; GlaxoSmithKline Vaccines) containing the WHO recommended strains for the 2011–2012 season in the ...
(aged 9–64 years and at high-risk of complications) [8]; furthermore, for individuals aged 65 or older, adjuvanted QIV (aQIV) was cost-saving compared with high-dose (HD)-QIV [3], and adjuvanted trivalent influenza vaccine (aTIV) was found to be cost-effective compared with TIV [...
A/H1N1, A/H3N2, and one (TIVs) or both (QIVs) B strains; adjuvant TIVs or high-dose QIVs; and a live attenuated quadrivalent influenza vaccine nasal spray (LAIV). Recommended vaccines vary by age group, with QIVs recommended in infants aged 6–23 months, QIVs or LAIV for children...