一、前言 某些非抗心律失常药物具有使心脏复极化延迟的不良 作用,在心电图上表现为 QT/QTc 间期延长,可能导致尖端 扭转型室性心动过速(Torsadede Pointes,TdP)。TdP 心电图 表现为快而不整齐的 QRS 波,振幅极性围绕等位线发生周 期性扭转。TdP 反复发作可能导致晕厥,诱发恶性心律失常 甚至进展为室颤而猝死。QT...
11. Brooks L, Dolton M, Langenhorst J, Yoshida K, Lien YT (Kayla), Malhi V, et al. Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug‐induced heart rate chan...
为了比较ECG不同时间点的QT间期,必须使用公式根据心率对QT间期进行校正,获得的数字称为“校正QT”(QTc),应用于指导临床决策。WHO建议对使用影响QT间期药物的患者采用心电图来监测QT间期,并建议优先选择Fridericia校正法[QT interval corrected for heart rate(Fridericia method),QTcF]对QT间期进行校正。目前,大多数心...
Objective: To compare QTc duration and increased heart rate in patients with cirrhosis with non- cirrhotic controls. Design: Cross-sectional analytical study. Place and Duration of Study: Medical Unit 1 Allied Hospital Faisalabad between 1st March 2011 to 30th August 2011. Patients and Methods: 50...
Results:Heart rate (P= .073), QT interval (P= .432) and QTc interval (P= .179) were similar before and after thyroid surgery. Tp-e interval (84.6 ± 13.1 vs 77.2 ± 10.9; P= .031), Tp-e/QT ratio (0.23 ± 0.04 vs 0.21 ± 0.04; P< .001), Tp-e/QTc ratio (0.21± 0.04...
11. Brooks L, Dolton M, Langenhorst J, Yoshida K, Lien YT (Kayla), Malhi V, et al. Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug‐induced heart rate changes. Clin Transl Sci. 2023 Feb 22;16(5):823–34. ...
WHO建议对使用影响QT间期药物的患者采用心电图来监测QT间期,并建议优先选择Fridericia校正法[QT interval corrected for heart rate(Fridericia method),QTcF]对QT间期进行校正。目前,大多数心电图机可使用校正公式自动生成QT值和QTc值,建议使...
Input the patient's heart rate in beats per minute. Choose QTc Formula and then click on the "Calculate" button to generate the corrected QT interval (QTc) figure*. QTc Calculator QT Interval, QT: Heart Rate, HR: bpm QTc Formula: Results QTc Formula: QTc = QT × RR -1/2, RR ...
Internal validation of the model was performed using 1 000 enhanced Bootstrap method, and the predictive value, calibration and clinical utility of the model were comprehensively assessed using receiver operating characteristic (ROC) curve, calibration curve, clinical decision curve (DCA) and clinical ...
Objective: To compare QTc duration and increased heart rate in patients with cirrhosis with non- cirrhotic controls. Design: Cross-sectional analytical study. Place and Duration of Study: Medical Unit 1 Allied Hospital Faisalabad between 1st March 2011 to 30th August 2011. Patients and Methods: 50...