QD Diffucaps® Drug Delivery Systems for Weakly Basic Pharmaceutical ActivesLack of compliance to dosing regimens is widespread largely dueto complicated regimens (e.g. too many medications, too frequent dosing) and swallowing difficulties. Eurand's Diffucaps(R) technology enables the development of...
Dosing intervals for slow-release theophylline preparations depend on the rate of formulation absorption, the rate of patient elimination, and clinically acceptable fluctuations in serum concentration. Three products, two new to the United States market, have received approval by the Food and Drug Admin...
Seventy-eight patients with moderate to severe AD were included in the study, randomly assigned to three groups, each receiving a different dosing regimen. The first three weeks involved dose titration, followed by a full-dose treatment period of nine weeks, with a total observation p...
BID dosing. Conclusions In ACS patients, no clinically meaningful differences on adherence measures were observed between QD versus BID dosing formulations over a 12 month follow-up period. Results indicate potential opportunities to improve persistency with chronic therapies in ACS patients....
#8 Using any sulfa-drug off label: The sulfonamide (“sulfa”) drugs may legally only be used exactly according to label instructions. Recent FDA investigations residues suggest that over-dosing sulfa boluses (Albon) or giving intravenous sulfa products (Di-methox) off-label in the muscle or ...
25% were due to hematologic toxicity and 14% due to non-hematologic toxicity; 28% required a dose reduction of which 13% were due to hematologic toxicity and 6% due to non-hematologic toxicity; the remainder of dose interruptions and reductions were due to other (including dosing error) or ...
[10]Steinberg BA, Shrader P, Thomas L, et al. Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes: The ORBIT-AF II Registry[J]. J Am Coll Cardiol, 201, 68(24): 2597-604. [11]Wang KL , Giugliano R, Goto S, et al. Standard versus low dose non...
Super-dosing PhytasePackage and StorageSolid Form:25kg Compound bag.Sealed storage in original package under 25ºC for 12 months for solid form.Avoid sunshine, rain, high temperature and high humidity during storage.Qingdao Rofeeds Biotech Co Ltd(Formerly Qingdao ...
Although proven drug hypersensitivity attributable to spironolactone is very rare, when allergic manifestations have occurred in a patient who may require readministration of spironolactone, we believe that the suggested protocol for test-dosing be considered 展开 ...
[2] Kassam AS, Cunningham EA, Musco SE. Dangers of rapid dosing: a case of dose-dependent drug-induced liver injury from duloxetine. Prim Care Companion CNS Disord. 2019;21(2):18l02333. [3] 李凌江,马辛. 中国抑郁障碍防治指南(第二版)[M]. 中华医学电子音像出版社. 2015. ...