Q fever (QF) and Rift Valley fever (RVF) are endemic zoonotic diseases in African countries, causing significant health and economic burdens. Accurate prevalence estimates, crucial for disease control, rely on robust diagnostic tests. While enzyme-linked immunosorbent assays ...
We used reference laboratory testing data to better understand diagnostic testing practices for Q fever in the United States. On average 12,821 serology specimens were tested for Q fever by IFA annually by participating laboratories from 2012 to 2016. When considering the other laboratories offering ...
5]. The cut-off for serological titres was first established in 1994 [44] but has been revised recently [5]. The diagnosis of Q fever is performed using different methods: a complement fixation test with commercially available antigen preparations...
The Q fever skin test is used to measure cell-mediated immunity to Coxiella burnetii in pre-vaccination screening to exclude individuals with pre-existing immunity. We investigated whether this in-vivo test influences subsequent measurements of immune response. We assessed the humoral and cellular imm...
The present invention relates to a method for diagnosing the Q-fever status in a subject, the method comprising the steps of: (a) obtaining a sample from said subject, (b) contacting said sample with a source of a Coxiella burnetiiantigen and (c) determining the profile of expression level...
Q fever is an acute infectious disease caused by Coxiella burnetii. The infection has been reported from all continents and occurs in sporadic and epidemic forms. Human infection is usually acquired by inhalation of the organisms from the tissues of infe
Potential serodiag- nostic markers for Q fever identified in Coxiella burnetii by immuno- proteomic and protein microarray approaches. BMC Microbiol 2012;12:35.Xiong XL, Wang XL, Wen BH. Potential serodiagnostic mark- ers for Q fever identified in Coxiella burnetii by immunopro- teomic and ...
We aimed to identify and test biomarkers in order to improve discriminative power of the diagnostic tests and monitoring of chronic Q fever. We performed a transcriptome analysis onC. burnetiistimulated PBMCs of 4 healthy controls and 6 chronic Q fever patients and identified genes that were most...
The ELISA proved to be an excellent diagnostic test for chronic Q fever. It distinguished negative from positive reactions clearly, and results were highly reproducible. The reading is objective, and the test is simple to perform and more sensitive than the IFA and complement fixation tests. The...
Investigation and Diagnostic Centre WallacevilleNew Zealand Veterinary JournalKittelberger R, Mars J, Wibberley G, Sting R, Henning K, Horner GW, Garnett KM, Hannah MJ, Jenner JA, Piggott CJ, O'Keefe JS (2009): Comparison of the Q fever comple- ment fixation test and two commercial enzyme...