Low vitamin B-6 status, based on plasma concentrations of pyridoxal-5-phosphate (PLP), has been identified in inflammatory diseases, including cardiovascular disease, rheumatoid arthritis, inflammatory bowel disease, and diabetes. Our objective was to examine the association between plasma PLP and ...
[4] Nonstandard abbreviations: ALP, alkaline phosphatase; PLP, pyridoxal 5'-phosphate; PA, pyridoxic acid; HPP, hypophosphatasia; TNSALP, tissue-nonspecific isoenzyme of alkaline phosphatase; PPi, inorganic pyrophosphate. A Man with Recurrent Fractures and Foot Pain Selhub, "Plasma pyridoxal 5'-phos...
Pyridoxal 5′-phosphate (PLP), the principal circulating form of vitamin B6 (B6), is elevated in the plasma of individuals with hypophosphatasia (HPP). HPP is the inborn-error-of-metabolism caused by loss-of-function mutation(s) of ALPL, the gene that encodes the "tissue-nonspecific" ...
Pyridoxal 5'-phosphate (PLP), the major coenzyme form of vitamin B6, is known to have antisickling properties in vitro. Recently, low plasma PLP levels were reported in a group of adults with sickle cell anemia. We measured the plasma PLP levels in a group of 55 asymptomatic nontransfused...
A new fluorometric method for the de- termination of pyridoxal 5#-phosphate. Biochim Biophys Acta 1973; 304:765-73.Srivastava, S. K. & Beutler, E. (1973) A new fluorometric method for the determination of pyridoxal 5’-phosphate. Biochim. Biophys. Acta 304 , 765–773....
We have demonstrated that pyridoxal 5′-phosphate (PLP), an active form of vitamin B6, inhibits formation of advanced glycation end-products (A... S Nakamura,H Li,A Adijiang,... - 《Nephrol.dial.transplant》 被引量: 67发表: 2007年 A simple enzymic assay for pyridoxal phosphate - ...
Intracellular interaction of the pyridoxal 5-phosphate (PLP) form of aspartate aminotransferase (AspAT) with vitamin B-6 and antagonists of vitamin B-6 in rabbit erythrocytes was measured in situ. In the erythrocytes, about 75% of the total AspAT was saturated with PLP. On the basis of the...
2 Although the routes of de novo pyridoxal 5′-phosphate (PLP) biosynthesis have been well described, studies of the engineering of an intracellular PLP supply are limited, and the effects of cellular PLP levels on PLP-dependent enzyme-based whole-cell biocatalyst activity have not been described...
The development of a simple enzymatic method for the determination of blood and plasma pyridoxal 5′-phosphate (PLP) using pig heart apo-aspartate transami... Ratree,Singkamani,D,... - 《Annals of Clinical Biochemistry》 被引量: 355发表: 1986年 Reconstitution and biochemical characterization of...
A sensitive spectrofluorimetric method for the estimation of pyridoxal 5'-phosphate (PLP) in human serum is described. The specificity is based on the selective oxidation of PLP to 4-pyridoxic acid 5'-phosphate with potassium cyanide. Separation of the highly fluorescent 4-pyridoxic acid 5'-...