Stability:Stable. Flammable. Incompatible with strong oxidizing agents, strong acids. InChIKeyJUJWROOIHBZHMG-UHFFFAOYSA-N LogP0.64 at 20℃ CAS DataBase Reference110-86-1(CAS DataBase Reference) IARC2B (Vol. 77, 119) 2019 NIST Chemistry ReferencePyridine(110-86-1) ...
Where SiO2 has strong covalent bonds between molecules, SO3 only has weak van der waals intermolecular forces holding its molecules together. Since covalent bonds require more energy to overcome than van der waals,SiO2 requires a higher temperature than SO3 to melt, thus SiO2 has a higher meltin...
Pyridine is a weak base (pKa= 5.25); a 0.2 M solution has a pH of 8.5 (HSDB 1988). Its carbon atoms are deactivated towards electrophilic substitution. This is especially true in acidic media, where salts form at the nitrogen. It does, however, readily undergo nucleophilic substitution, pr...
Though pyridine is a useful compound, utilized in every potential field. But if consumed by humans, it might prove dangerous. The severity depends upon the amount of consumption and mode. Pyridine can enter the human body while breathing, drinking, or consuming anything that has the presence of...
Weak depolarization of plasma membrane by 250 μM 4-AP failed to cause stable changes in membrane potential (Fig. 2a), but transporter-mediated glutamate release facilitated during plasma membrane depolarization at more appreciable 4-AP concentrations, may partially contribute to the total ...
(1) Catalytic synthesis of tri-O-acetylated erythromycin using DMAP and weak base anion exchange resin composite catalyst reaction, which is simple, fast and has high yield compared with the usual methods. The reaction time is reduced from 10 days to 10 hours, and the yield is as high as ...
On the other hand, substitution with strong electronegative nitro moiety at the para position of the phenyl ring (4g) leads to a reduction in activity which could be due to the polar nature of this group. Para-methyl substitution (4c) displayed good activity against all the tested cancer ...
Increase in [Ca2+]iaffects wide range of cellular signalling pathways, vesicle trafficking and makes a strong impact on the observed processes, particularly, on transport of neurotransmitters at the level of plasma membrane and synaptic vesicles. These results require careful consideration in future exp...
such as the hydrogen bond can facilitate the ubiquitous ultra-weak photon emission mode9,10. In addition, the fluorescent phenomena originated from de-excitation process are very widespread in all sorts of scale of biological systems11. Therefore, the dynamic mechanism of hydrogen bond will be exte...
Thus, KDR undergoes strong ligand-dependant tyrosine phosphorylation in intact cells, whereas flt-1 displays a weak response. Thus, binding to KDR is a critical requirement for induction of the full spectrum of VEGF-mediated biological responses. In vivo, VEGF plays a central role in ...