ChemInform Abstract: Pyrazolo(3,4-d)pyrimidines; Adenosine Receptor Selectivityfused pyrimidine derivativespharmacology, medicinal chemistry, vaccines, serumsChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a...
Synthesis of pyrazolo[3,4-d]pyrimidine analogues of the potent antitumor agent N-f4-[2-(2-amino-4-(3H)-oxo-7H-pyrolo[2,3-d]pyr- imidin-5-yl)ethyl]benzolg-l-gultamic acid (LY231514). Tetrahedron 1992, 48 (37), 8089-8100....
(2-phenoxy-pyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo-[1,2-a]pyrazol-1-one; 2-(4-Fluorophenyl)-3-[2-(4-fluorophenoxy)pyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo-[1,2-a]pyrazol-1-one; 2-(4-Fluorophenyl)-3-[2-(2,6-difluorophenoxy)pyrimidin-4-yl)-6,7-dihydro-5H-pyrazolo-[...
Sznaidman.Guanine, Pyrazolo[3,4-d]pyrimidine, and Triazolo[4,5-d]pyrimidine (8-Azaguanine) Phosphonate Acyclic Derivatives as Inhibitors of Purine Nucleoside Phosphorylase.Journal of Medicinal Chemistry. 1996Beauchamp, L. M., Tuttle, J. V., Rodriguez, M. E., and Sznaidman, M. L., " ...
Novel 3-alkoxy-1 H -pyrazolo[3,4- d ]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors[J] . Richard Ducray,Peter Ballard,Bernard C. Barlaam,Mark D. Hickinson,Jason G. Kettle,Donald J. Ogilvie,Catherine B. Trigwell.Bioorganic & Medicinal Chemistry Letters . 2007 (3)...
A short synthesis of 4substituted 1-(hydroxyalkyl)-1H-pyrazolo[3,4-d]pyrimidines. Tetrahedron - Zacharie, Connolly, et al. - 1996 () Citation Context ...yanoethylene (1c). R CN R CN N N Ar N N NH 2 R 1 CN + Me NHNH 2 (4) (1) (2) R CN a: R = R 1 = SMe b: ...
ChemInform Abstract: Synthesis of 2′,3′‐Anhydronucleosides of Pyrazolo(3,4‐d)pyrimidine as Antiviral Agents.nucleic acidsring closure reactionspharmacology, medicinal chemistry, vaccines, serumsChemInform is a weeklying Service, delivering concise information at a glance that was extracted from about...
ChemInform Abstract: Synthesis and Biological Activity of 2′‐Fluoro‐D‐arabinofuranosylpyrazolo[3,4‐d]pyrimidine Nucleosides.nucleic acidspharmacology, medicinal chemistry, vaccines, serumsChemInform is a weeklying Service, delivering concise information at a glance that was extracted from about 100 ...
ChemInform Abstract: A Short Synthesis of 4-Substituted 1-(Hydroxyalkyl)-1H-pyrazolo(3,4-d) pyrimidinesdoi:10.1002/chin.199624158pyrimidine derivativespharmacology, medicinal chemistry, vaccines, serumsChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted...
N.; Orlov, V. D.; Musatov, V. I. New Oxidation-Reduction Transformation of Derivatives of 1,10b- Dihydro-1H-pyrazolo[1,5-c]-1,3-benzoxazine and 7,12-Dihydro-6H- [1]benzopyrano[4,3-d]-1,2,4-triazolo[1,5-a]pyrimidine. Chem. Hetero- cycl. Compd. 2001, 37, 1312-1313....