早在20世纪70年代末80年代初,有病例报告及小型研究显示,CA(Cardiac amyloidosis, CA)患者的心脏对99mTc-PYP有独特的摄取模式,有助于心脏淀粉样变的诊断。但是,由于早期研究没有区分转甲状腺素蛋白心脏淀粉样变(transthyretin cardiac amyloidos...
参考文献: 1.Felix D Nguyen, Mario Rodriguez, et al. Misconceptions and Facts About Cardiac Amyloidosis.Am J Cardiol. 2021 Dec 1:160:99-105. doi: 10.1016/j.amjcard.2021.08.045. Epub 2021 Oct 3. 全面工作 传播矩阵 FOLLOW US 苏州工业园区东方华夏心血管健康研究院 电话:0512-68295918 邮箱:info...
Transthyretin-related cardiac amyloidosis (ATTR) amyloidosis is an aggressive, rapidly progressive, and fatal disease, for which several promising therapies are in development. This condition is frequently underdiagnosed because of the limited specificity of echocardiography and the traditional requirement for...
参考文献: 1.Felix D Nguyen, Mario Rodriguez, et al. Misconceptions and Facts About Cardiac Amyloidosis.Am J Cardiol. 2021 Dec 1:160:99-105. doi: 10.1016/j.amjcard.2021.08.045. Epub 2021 Oct 3. 全面工作
Optimizing cardiac amyloidosis assessment: utility of 1-h and 3-h99mTc-PYP imagingdoi:10.1186/s40001-023-01629-yATTR transthyretin cardiomyopathyNuclear imaging99mTc-PYPIncubation timeTransthyretin amyloid cardiomyopathy (ATTR-CM), characterized by the extracellular deposition of an insoluble amyloid protein...
cardiac amyloidosisheart failurepreserved ejection fractionTransthyretin amyloid deposition is present in 17% of autopsies of patients with heart failure and a preserved ejection fraction (HFpEF). "Technetium-pyrophosphate scintigraphy (~99mTc-PYP) is sensitive and specific to diagnose cardiac transthyretin ...
AmyloidosisBackground:Cardiac amyloidosis (CA) is a Hypertrophic Cardiomyopathy (HCM) mimic. Technetium labeled pyrophosphate (Tc-PYP) scan provides a rapid & non-invasive means for identifying ATTR-type CA with 99% sensitivity and specificity. We present 2 patients who were referred to HCM clinic...
PYP or DPD and HDP for cardiac amyloidosis one for all, all for one.doi:10.1007/s12350-019-01728-6Francesco CappelliChiara GalliniFederico PerfettoSpringer Science and Business Media LLC
Abstract 15674: Utilization Rates of Follow-Up Testing With Pyp Scan and Cardiac Mri, and Clinical and Demographic Determinants of Their Use Among Patients With Echocardiographic Features of Cardiac Amyloidosis: A Population-Based Case Control Study...
Technetium pyrophosphate (Tc-99m-PYP) scintigraphy is a simple and widely available radiotracer useful to differentiate transthyretin from light-chain amyloidosis in patients with advanced cardiac amyloidosis. We examined the utility of serial Tc-99m-PYP scanning to quantify amyloid burden over time ...