PYD and CARD domain containing (PYCARD; ASC)In vitro and mouse studies suggest depleting extracellular ASC particles could help treat inflammatory diseases.Science-Business eXchangedoi:10.1038/scibx.2014.898None
More recently, non-NLR type, pyrin-domain (PYD)-containing proteins such as pyrin or absent in melanoma2 (AIM2) were also proposed to form caspase-1-activating inflammasome machinery with apoptosis-associated speck-like protein containing a CARD (ASC), an essential adaptor molecule. Inflammasome ...
BTK affected apoptosis-associated speck-like protein containing a CARD (ASC) speck formation and caspase-1 cleavage and interacted with NLRP3 and ASC. S aureus infection control in vivo and IL-1β release from cells of patients with Muckle-Wells syndrome were impaired by ibrutinib. Notably, IL...
品牌:Wako CAS No.: 储存条件:-20℃ 纯度:– 产品编号 (生产商编号) 等级规格运输包装零售价(RMB)库存情况参考值 011-21911 for Immunochemistry100 ul–3,960.00–– * 干冰运输、大包装及大批量的产品需酌情添加运输费用 * 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动,...
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Pyd and Card domain containing (Pycard; Asc); Nlr family, pyrin domain containing 3 (Nlrp3; Nalp3)Cell culture and animal studies suggest that targeting Nalp3 and Asc in macrophages might help prevent tissue damage associated with silicosis and other pulmonary fibrotic disorders.Science-Business ...