In addition, as set out above, the MDR1 protein is known to be expressed at the blood-brain barrier and when incorporated into the above described humanised mouse will provide a truly representative scenario of the uptake of drugs/xenobiotics into and out of the brain in man. According a ...
While alterations in PXR gene expression are known to play a significant role in the prognosis of PSC, a study by Poupon and collaborators demonstrated that the genetic background of PXR, specifically a single nucleotide polymorphism (SNP) C/A in exon 9 of 3′-UTR of NR1L2/PXR, is ...
through inhibition of the NF-κB signaling pathway20,21. In addition, a heightened sensitivity to oxidative toxicants was noted in both cell and mouse models uponPXRactivation22. With improvement of genetic research methodology, a large number of single nucleotide polymorphisms (SNPs) in thePXRgene...
It adopts a 7-inch touch screen, the latest ARM7 single-chip microcomputer, high-speed AD acquisition circuit, and is equipped with background management software. It overcomes many shortcomings of similar domestic products (see Table 1), and its cos...
Leverage your image gallery to expand on the product’s story through high-resolution product images, shot on a white background for a clear and distraction-free appearance. Include lifestyle images that showcase the product in use, and/or infographics that highlight important features...