In adults, the trigger for acute ITP may not be obvious. The first sign of the illness may be a red or purple skin rash on the legs or abnormal bruising after only minor trauma. There also may be small areas of bleeding or "blood blisters" on the surface of the lips or gums, and...
Studies conducted by Hung et al [36] identified patients aged 20 years and older, male gender, bloody stools, and a rash persisting beyond 1 month as adverse prognostic factors for HSP. Schaier et al [37] reported that older patients with HSP presenting with renal involvement exhibited poorer...
Any rash in which blood cells leak into the skin or mucous membranes, usually at multiple sites. Purpuric rashes often are associated with disorders of coagulation or thrombosis. Pinpoint purpuric lesions are called petechiae; larger hemorrhages into the skin are called ecchymoses. Synonym: peliosis...
It rarely presents with significant pericardial disease, especially in adults, and is a rare entity with only a few reported cases. Case Description A 49 year old Male presented with a two month history of progressive dyspnea, polyarthralgia, fatigue, and skin rash. Physical exam showed cardiac...
How Long Does Henoch-Schönlein Purpura Last? In 94% of children and 89% of adults with IgA vasculitis, the disease goes away on its own. The rash and joint pain usually disappear after 4 weeks without causing any permanent damage. The rash comes back in one out of three people w...
Living in cold weather A family history of HSP What are the signs and symptoms of HSP? A purple rash (purpura) is the most common sign of HSP. The rash may feel bumpy. The rash may first appear on your legs, arms, or buttocks. It may spread to your chest, back, or face. You ...
Its radiological signs can be observed in grey and white matter at the posterior region of the cerebral hemispheres. HSP should be considered in children with PRES in the presence of rash, joint and gastrointestinal symptoms. We reported a 5-year-old patient who developed acute renal failure ...
HSP, a vasculitic syndrome characterized by skin rash, abdominal colic, joint pain and glomerulonephritis, was first described in 1801 by Dr. William Heberden [4]. The syndrome is mainly a disease of early childhood with most cases presenting by 10 years of age. It is uncommon in adults over...
[138]. Because the telltale rash may not occur until after the onset of other symptoms, early diagnosis may be challenging in some cases[139,140]. Additionally, women who have had HSP as a child are more likely to have proteinuria or hypertension during pregnancy, even the absence of ...
Schönlein-Henoch purpura is a distinctive clinical syndrome. The skin lesions consist of recurrent purpuric papules, sometimes necrotizing, on the lower limbs. Spread of the rash to the trunk seems to be a predictive factor for renal involvement [6]. Initial symptoms may be accompanied by fev...