This allowed us to catalog the true function-perturbing mutations in each line. We can apply this same approach here. Approximately 300 non-synonymous, 20 twenty gene-disruption (e.g. nonsense, splice site) and more than 10,000 silent-site or non-coding mutations per individual can be ...
The prominent and rapidly expanding role of mass spectrometry (MS) in the physical and biological sciences can be attributed in part to the versatility afforded by the growing catalog of available ionization methods. Many ionization techniques of increasing importance operate at elevated or atmospheric ...